[Results of surgical treatment of stage I lung cancer].
[Results of surgical treatment of stage I lung cancer].
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I期肺癌手术治疗结果[J].
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
Y. Arano
中科院分区：
文献类型：
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作者：
J. Shimizu;Y. Watanabe;M. Oda;Y. Hayashi;Y. Ota;K. Morita;Y. Arano
本研究对已切除的I期肺癌的生存曲线和影响预后的背景因素进行了回顾。 1973年1月至1989年9月，金泽大学医院共收治了735例原发性肺癌患者，其中I期肺癌288例（39.2%）。所有I期肺癌患者术后累计5年生存率为61.7%。与生存率最相关的背景因素是T因素。根据T因子的5年生存率如下：T1N0M0； 74.5%，T2N0M0； 53.8%。他们之间的生存率存在显着差异（p<0.05）。在这 288 例病例中，与 120 例鳞状细胞癌病例相比，128 例腺癌病例的生存期显着延长 (p < 0.01)。女性 I 期肺癌患者的 5 年生存率显着优于男性 I 期肺癌患者 (p < 0.01)。当按原发肿瘤的倍性模式比较生存率时，二倍体肿瘤患者的生存率明显高于非整倍体肿瘤患者（p < 0.05）。建议辅助治疗可能会提高 I 期肺癌患者的生存率，尤其是 T2N0M0 分类的患者。
In this study, survival curves and background factors affecting prognosis of resected stage I lung cancer were reviewed. A total of 735 patients with primary lung cancer, including 288 cases (39.2%) of stage I lung cancer, were surgically treated at Kanazawa University Hospital from January 1973 through September 1989. The cumulative 5-year survival rate after operation for all cases of stage I lung cancer was 61.7%. The background factor which was most concerned with the survival rate was the T factor. The 5-year survival rates according to T factor were as follows: T1N0M0; 74.5%, T2N0M0; 53.8%. There was significant difference of survival rates between them (p < 0.05). Of these 288 cases, 128 cases with adenocarcinoma showed significant prolonged survival when compared to 120 cases with squamous cell carcinoma (p < 0.01). In female patients with stage I lung cancer the 5-year survival rate was significantly better than in male patients with stage I lung cancer (p < 0.01). When the survival rates were compared by ploidy pattern of the primary tumor, patients with diploid tumors showed significantly better survival than those with aneuploid tumors (p < 0.05). It is possible that adjuvant therapy is recommended to improve the survival rate of patients with stage I lung cancer, especially, those in the T2N0M0 classification.