Changes in Central Corneal Thickness With Air-Puff-Induced Corneal Deformation Using a Method to Correct Scheimpflug and Refractive Distortion.
Changes in Central Corneal Thickness With Air-Puff-Induced Corneal Deformation Using a Method to Correct Scheimpflug and Refractive Distortion.
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采用一种校正Scheimpflug成像和折射畸变的方法研究空气脉冲诱导角膜变形时中央角膜厚度的变化
DOI：
10.3928/1081597x-20210219-01
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发表时间：
2021-06
期刊：
影响因子：
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通讯作者：
Roberts CJ
中科院分区：
文献类型：
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作者：
Okon MD;Ma Y;Liu J;Roberts CJ
建立一种测定在最高凹陷（HC）状态下受空气脉冲变形的角膜的中央角膜厚度（CCT）和前房深度（ACD）的方法。
对155名参与者的155只眼睛使用Corvis ST（奥culus光学仪器有限公司）进行成像，对凸形预变形（PRE）角膜的Scheimpflug图像实施芬克屈光矫正方法。随后针对变形的HC状态对该方法进行了改进。导出每个参与者角膜在PRE和HC状态下的追踪边缘。选择图像中晶状体可见的10名参与者以确定两种状态下的ACD。角膜追踪边缘和晶状体上的中心点分别用于确定未矫正的CCT和ACD。
平均未变形的CCTPRE显著低于变形的CCTHC（分别为584±31和626±34μm）（P <.0001）。两种状态之间矫正后的ACD未发现显著差异。在两种变形状态下，矫正后的CCT和ACD均显著大于相应的未矫正值（P <.0001）。发现CCT的百分比变化与HC处弧长的变化相关（P <.0001）。
使用改进的芬克方法可以矫正HC状态下Corvis ST图像的失真。与PRE状态相比，发现HC状态下CCT增加。角膜变形过程中的CCT变化在角膜压缩反应的研究中可能很重要。
To establish a method to determine central corneal thickness (CCT) and anterior chamber depth (ACD) of an air-puff–deformed cornea at the highest concavity (HC) state. The Fink method for refractive correction of Scheimpflug images of a convex pre-deformed (PRE) cornea was implemented for 155 eyes of 155 participants imaged with the Corvis ST (Oculus Optikgeräte GmbH). This method was subsequently modified for the HC state of deformation. The tracked edges of each participant’s cornea were exported at the PRE and HC states. Ten participants who had a visible crystalline lens in the image were selected to determine ACD in both states. The center points on the corneal tracked edges and lens were used to determine uncorrected CCT and ACD, respectively. Average undeformed CCTPRE was significantly lower than deformed CCTHC (584 ± 31 and 626 ± 34 μm, respectively) (P < .0001). No significant difference was found for the corrected ACD between the two states. Corrected CCT and ACD were significantly greater than the corresponding uncorrected values for both deformation states (P < .0001). Percent change in CCT was found to be correlated to change in arc length at HC (P < .0001). Distortion in Corvis ST images at the HC state can be corrected using a modified Fink method. CCT was found to increase in the HC state, compared to the PRE state. The CCT change during deformation may be important in the study of the compressive response of the cornea.