No influence of GB virus C replication on the prognosis in a cohort of HIV-1-infected patients
No influence of GB virus C replication on the prognosis in a cohort of HIV-1-infected patients
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DOI：
10.1097/00002030-200212060-00017
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发表时间：
2002-12-06
期刊：
影响因子：
3.8
通讯作者：
Lidman, C
中科院分区：
文献类型：
--
作者：
Birk, M;Lindbäck, S;Lidman, C
在HIV-1感染者中合并感染GB病毒C（GBV-C）可能对疾病结局产生有益影响。我们随访了157例HIV-1感染患者，其血清转换日期定义在+/-1年内，中位时间为7年。在这些患者中，36例（23%）GBV-C RNA阳性。生命表分析显示，有或无GBV-C病毒血症患者的结局变量无显著差异。终点为CD 4 T淋巴细胞计数≤ 200个细胞/穆尔、AIDS诊断和AIDS相关死亡。
Co-infection with GB virus C (GBV-C) in HIV-1-infected individuals could have a beneficial influence on disease outcome. We followed 157 HIV-1-infected patients with seroconversion dates defined within +/-1 year for a median of 7 years. Of these patients, 36 (23%) were positive for GBV-C RNA. Life-table analyses showed no significant difference in outcome variables between patients with or without GBV-C viraemia. Endpoints were CD4 T lymphocyte count of 200 cells/mul or less, AIDS diagnosis and AIDS-related death.