The role of gastric secretion in post‐diverted pancreatic hypersecretion in conscious rats.
The role of gastric secretion in post‐diverted pancreatic hypersecretion in conscious rats.
复制标题
胃分泌在清醒大鼠转移后胰腺分泌过多中的作用。
DOI：
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发表时间：
1982
期刊：
影响因子：
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通讯作者：
H. Sarles
中科院分区：
文献类型：
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作者：
A. Noda;D. F. Magee;H. Sarles
1. In rats prepared with chronic external pancreatic fistulae, gastric fistulae and choledocho‐enterostomy, the volume and protein secretion of pancreatic juice was measured. 2. The pancreatic secretion of water and protein after juice diversion was significantly lower when the gastric fistula was open than when closed. Secretion was abolished after atropine, with the fistula open and in animals with ligated pylori. 3. Intraduodenal HCl significantly raised juice volume and protein in animals with diverted juice when the gastric fistula was open. 4. Soybean trypsin inhibitor produced a significantly smaller elevation of juice volume and protein when the gastric fistula was open. 5. It is concluded that the initial hypersecretion of pancreatic juice and protein, following its diversion from the duodenum, is a consequence of the entry of gastric juice into the intestine.
