A hybridisation-dependent membrane-insertable amphiphilic DNA
A hybridisation-dependent membrane-insertable amphiphilic DNA
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DOI：
10.1039/c5ob01761k
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发表时间：
2015-01-01
影响因子：
3.2
通讯作者：
Nakatani, K.
中科院分区：
文献类型：
--
作者：
Dohno, C.;Matsuzaki, K.;Nakatani, K.
我们合成了一种新型的可插入膜的两亲DNA。两亲DNA的一端有一个由辛基磷酸三酯键组成的九个核苷酸的疏水区。两亲性DNA通过插入疏水区与脂膜结合；互补DNA链的存在促进了这一过程。
We synthesised a novel membrane-insertable amphiphilic DNA. The amphiphilic DNA had a nine-nucleotide hydrophobic region at one end consisting of octyl phosphotriester linkages. The amphiphilic DNA bound to the lipid membrane by inserting the hydrophobic region; this process was facilitated by the presence of the complementary DNA strand.