Antibiotic resistance of Staphylococcus aureus isolated from community and nosocomial infections in Casablanca.

Antibiotic resistance of Staphylococcus aureus isolated from community and nosocomial infections in Casablanca.
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DOI:
10.1016/s0399-077x(01)00165-2
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发表时间:
2001-01-01
影响因子:
5
通讯作者:
Benbachir, M
Benbachir, M
中科院分区:
医学4区
文献类型:
--
作者:
Belabbès, H;Elmdaghri, N;Benbachir, M

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目的:测定卡萨布兰卡IbnRochd大学医院两个时期分离的156株社区获得性金黄色葡萄球菌和189株医院获得性金黄色葡萄球菌对11种抗生素的耐药模式。材料和方法:用6 mg/L苯唑西林琼脂筛选技术进行甲氧西林耐药检测,用NCCLS纸片扩散法研究对其他抗生素的耐药。结果:156株社区获得性金黄色葡萄球菌和189株医院获得性金黄色葡萄球菌对11种抗生素的耐药模式。社区和医院分离株对甲氧西林的耐药率分别为1.9%和45%。MRSA多重耐药(庆大霉素84.7%,复方新诺明51.2%,红霉素44.7%,夫西地酸45.9%,环丙沙星83.5%)。MRSA分离株主要在第一阶段从外科(46.2%)分离,在第二阶段从ICU(61%)分离。MRSA主要来源于血液(34.1%)、脓液(34.6%)和呼吸道(27.1%)。(C)2001年,Elsevier SAS科学与医学版。
Objective - The resistance patterns to 11 antibiotics of 156 community acquired and 189 nosocomial Staphylococcus aureus isolated during two periods at the IbnRochd University Hospital of Casablanca were determined.Material and methods - Defection of methicillin resistance was performed using the agar screen technique with 6 mg/L of oxacillin and resistance to other antibiotics was studied using the NCCLS disk diffusion method.Results - Methicillin resistance levels were 1.9% and 45% for community and nosocomial isolates respectively. MRSA isolates were multiresistant (gentamicin 84.7%, cotrimoxazole 51.2%, erythromycin 44.7%, fusidic acid 45.9%, ciprofloxacin 83.5%). MRSA isolates were mostly isolated from the surgery department (46.2%) during the first period and from the ICU (61%) during the second period. MRSA were isolated mainly from blood (34.1%), pus (34.6%), and respiratory tract (27.1%). (C) 2001 Editions scientifiques et medicales Elsevier SAS.