Oral and dental late effects in survivors of childhood cancer: a Children's Oncology Group report.
Oral and dental late effects in survivors of childhood cancer: a Children's Oncology Group report.
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儿童癌症幸存者的口腔和牙齿后期影响：儿童肿瘤小组报告。
DOI：
10.1007/s00520-014-2260-x
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发表时间：
2014-07
影响因子：
3.1
通讯作者：
Castellino, Sharon M.
中科院分区：
文献类型：
--
作者：
Effinger, Karen E.;Migliorati, Cesar A.;Hudson, Melissa M.;McMullen, Kevin P.;Kaste, Sue C.;Ruble, Kathy;Guilcher, Gregory M. T.;Shah, Ami J.;Castellino, Sharon M.
多模式治疗提高了儿童恶性肿瘤的生存率。儿童肿瘤学组《儿童、青少年和青年癌症幸存者长期随访指南》为从业人员提供了基于暴露和风险的建议，用于监测和管理距离完成治疗至少 2 年的无症状幸存者。这篇综述概述了儿科癌症幸存者口腔和牙齿迟发效应的病理生理学和风险，以及儿童肿瘤学组推荐的口腔和牙齿筛查的基本原理。通过 MEDLINE 对儿童癌症治疗的口腔和牙齿并发症进行了英文文献检索，检索时间涵盖 1975 年 1 月至 2013 年 1 月。基于文献综述的拟议指南内容得到了多学科生存专家小组的批准，并根据国家综合癌症网络“共识类别”系统的修改版本进行评分。儿童肿瘤学小组口腔牙科小组选择了 85 个相关引文。儿童癌症治疗可能会影响牙齿发育、唾液功能、颅面发育和颞下颌关节功能，使一些儿童癌症幸存者口腔和牙齿健康状况不佳的风险增加。此外，头颈放射和造血干细胞移植会增加随后口腔恶性肿瘤的风险。幸存者需要常规牙科护理来评估潜在的副作用并开始早期治疗。某些儿童癌症幸存者口腔和牙齿健康状况不佳的风险增加。及早识别口腔和牙齿发病情况并进行早期干预可以优化健康和生活质量。
Multi-modality therapy has resulted in improved survival for childhood malignancies. The Children’s Oncology Group Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancers provide practitioners with exposure- and risk-based recommendations for the surveillance and management of asymptomatic survivors who are at least 2 years from completion of therapy. This review outlines the pathophysiology and risks for oral and dental late effects in pediatric cancer survivors and the rationale for oral and dental screening recommended by the Children’s Oncology Group. An English literature search for oral and dental complications of childhood cancer treatment was undertaken via MEDLINE and encompassed January 1975 to January 2013. Proposed guideline content based on the literature review was approved by a multi-disciplinary panel of survivorship experts and scored according to a modified version of the National Comprehensive Cancer Network “Categories of Consensus” system. The Children’s Oncology Group oral-dental pan el selected 85 relevant citations. Childhood cancer therapy may impact tooth development, salivary function, craniofacial development, and temporomandibular joint function placing some childhood cancer survivors at an increased risk for poor oral and dental health. Addition ally, head and neck radiation and hematopoietic stem cell transplantation increase the risk of subsequent ma lignant neoplasms in the oral cavity. Survivors require routine dental care to evaluate for potential side effects and initiate early treatment. Certain childhood cancer survivors are at an increased risk for poor oral and dental health. Early identification of oral and dental morbidity and early interventions can optimize health and quality of life.
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影响因子：
4.3
作者：
Dahllof, Goeran
通讯作者：
Dahllof, Goeran
影响因子：
45.3
作者：
Bassal, M;Mertens, AC;Kadan-Lottick, NS
通讯作者：
Kadan-Lottick, NS
影响因子：
20.3
作者：
Armenian, Saro H.;Sun, Can-Lan;Bhatia, Smita
通讯作者：
Bhatia, Smita
影响因子：
6.2
作者：
Casillas, Jacqueline;Castellino, Sharon M.;Hudson, Melissa M.;Mertens, Ann C.;Lima, Isac S. F.;Liu, Qi;Zeltzer, Lonnie K.;Yasui, Yutaka;Robison, Leslie L.;Oeffinger, Kevin C.
通讯作者：
Oeffinger, Kevin C.
影响因子：
2.6
作者：
Baird, Kristin;Cooke, Kenneth;Schultz, Kirk R.
通讯作者：
Schultz, Kirk R.