The possible association between exposure to air pollution and the risk for congenital malformations

The possible association between exposure to air pollution and the risk for congenital malformations
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DOI:
10.1016/j.envres.2014.08.024
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发表时间:
2014-11-01
影响因子:
8.3
通讯作者:
Lerner-Geva, Liat
Lerner-Geva, Liat
中科院分区:
环境科学与生态学2区
文献类型:
--
作者:
Farhi, Adel;Boyko, Valentina;Lerner-Geva, Liat

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背景:在过去的十年中,越来越多的证据表明,暴露于空气污染可能与先天性畸形风险增加有关。目的:评估怀孕期间暴露于空气污染与自然受孕 (SC) 妊娠和辅助生殖技术 (ART) 妊娠后出生的婴儿先天性畸形之间可能存在的关联。 方法:这是一项历史队列研究,包含 216,730 名婴儿:207,825 名 SC 婴儿1997 年至 2004 年期间,8905 名 ART 受孕婴儿。空气污染数据,包括二氧化硫 (SO2)、颗粒物
Background: Over the last decade, there is growing evidence that exposure to air pollution may be associated with increased risk for congenital malformations.Objectives: To evaluate the possible association between exposures to air pollution during pregnancy and congenital malformations among infants born following spontaneously conceived (SC) pregnancies and assisted reproductive technology (ART) pregnancies.Methods: This is an historical cohort study comprising 216,730 infants: 207,825 SC infants and 8905 ART conceived infants, during the periods 1997-2004. Air pollution data including sulfur dioxide (SO2), particulate matter