A three step synthesis of 11-cycloheptylundecanoic acid, a component of the thermoacidophile Alicyclobacillus cycloheptanicus
A three step synthesis of 11-cycloheptylundecanoic acid, a component of the thermoacidophile Alicyclobacillus cycloheptanicus
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DOI：
10.3390/30200041
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发表时间：
1998-02-01
期刊：
影响因子：
4.6
通讯作者：
Mamdapur, VR
中科院分区：
文献类型：
--
作者：
Hassarajani, SA;Mamdapur, VR
从嗜热嗜酸菌脂环酸芽孢杆菌（Alicyclobacilluscycloheptanicus）的脂类中分离得到11-环庚基十一烷酸甲酯（1）。这涉及环庚基溴化镁和由10-十一烷酸制备的11-溴十一烷酸甲酯（2）之间的区域选择性格氏偶联。
A simple synthesis of the methyl ester of 11-cycloheptylundecanoic acid (1), isolated from the lipid fraction of the thermoacidofile, Alicyclobacillus cycloheptanicus has been developed. This involved regioselective Grignard coupling between cycloheptylmagnesium bromide and methyl 11-bromoundecanoate (2), prepared from 10-undecanoic acid.