Using the Palliative Performance Scale to Provide Meaningful Survival Estimates
Using the Palliative Performance Scale to Provide Meaningful Survival Estimates
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DOI：
10.1016/j.jpainsymman.2008.05.017
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发表时间：
2009-07-01
影响因子：
4.7
通讯作者：
Yang, Ju
中科院分区：
文献类型：
--
作者：
Lau, Francis;Downing, Michael;Yang, Ju
尽管使用姑息性表现量表（palliative Performance Scale， PPS）对接受姑息治疗的晚期癌症患者的生存预测有越来越多的知识，但这些文献主要关注疾病、性别和护理地点，而对于如何将这些知识应用于临床意义却知之甚少。为了解决这个问题，我们评估了一个包含6066名患者13年初始PPS评分的数据库，这些评分是由维多利亚临终关怀医院姑息治疗车团队在家中或姑息治疗单位销售的第一次评估时记录的。我们的研究结果再次证实了PPS是生存率的重要预测指标，PPS水平越高，生存时间越长。我们探索了生存时间分布、预期寿命表和生存nomogram作为协助估计姑息治疗中生存时间的三种潜在方法。Vile还评估了Kaplan-Meier生存曲线“鼻尾”精炼的概念，并观察到这种方法需要更多的研究。需要做更多的工作来更好地识别那些活得“比预期长”或死得“比预期早”的人，以便在与患者和家属讨论时提供临床效用。[J]中华口腔医学杂志，2009;38(1):1 - 4。(c) 2009年美国癌症疼痛缓解委员会。Elsevier Inc.出版。版权所有。
Although there is a growing body of knowledge on survival prediction in populations with advanced cancer receiving palliative care using the Palliative Performance Scale (PPS), this literature has focused on disease, gender, and care location, and le ss is known about how to apply such knowledge to be clinically meaningful. To address this issue, we evaluated a database comprising 13 years of initial PPS scores on 6066 patients, which were recorded on their first assessment by the Victoria Hospice palliative cart team in the home or palliative care unit selling. Our results reaffirmed PPS as a significant predictor of survival, with increasing survival times associated with higher PPS levels. We explored survival time distributions, a life expectancy table, and a survival nomogram as three potential ways to assist in estimating survival limes in palliative care. Vile also evaluated the concept of Kaplan-Meier survival curve "nose-tail" refinement, and observed that this approach requires more research. More work is needed to better identify those who live "longer than expected" or die "sooner than expected" to provide clinical utility in discussion with patients and families. J Pain Symptom Manage 2009;38:134-144. (c) 2009 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.