Investigation of doublecortin and calcium/calmodulin‐dependent protein kinase‐like‐1‐expressing cells in the mouse stomach

Investigation of doublecortin and calcium/calmodulin‐dependent protein kinase‐like‐1‐expressing cells in the mouse stomach
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小鼠胃中双皮质素和钙/钙调蛋白依赖性蛋白激酶样 1 表达细胞的研究

DOI:
10.1111/j.1440-1746.2009.06114.x
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发表时间:
2010
影响因子:
4.1
通讯作者:
Xinlan Huang
Xinlan Huang
中科院分区:
医学3区
文献类型:
--
作者:
Yan Zhang;Xinlan Huang

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背景和目的:由于缺乏明确的干细胞标记物,对损伤后干细胞的确切定位和命运的了解有限。 双皮质素和钙/钙调蛋白依赖性蛋白激酶样1(DCAMKL-1)是一种公认的肠和结肠干细胞标志物。我们的目的是鉴定胃上皮中表达DCAMKL-1的细胞,并分析胃粘膜损伤和修复过程中表达DCAMKL-1的细胞的命运。
Background and Aims:  For lack of a definite stem cell marker, there is limited knowledge of the precise location and fate of stem cells after injury. Doublecortin and calcium/calmodulin‐dependent protein kinase‐like‐1 (DCAMKL‐1) is a putative intestinal and colon stem cell marker. Our aim was to identify DCAMKL‐1‐expressing cells in the gastric epithelium and to analyze the fate of DCAMKL‐1‐expressing cells during gastric mucosal injury and repair.
胃上皮祖细胞生态位和酶原(主要)细胞谱系的分化。
DOI: 10.1016/j.ydbio.2008.10.025
发表时间: 2009-01-01
影响因子: 2.7
作者:
Bredemeyer, Andrew J.;Geahlen, Jessica H.;Weis, Victoria G.;Huh, Won Jae;Zinselmeyer, Bernd H.;Srivatsan, Subhashini;Miller, Mark J.;Shaw, Andrey S.;Mills, Jason C.
通讯作者: Mills, Jason C.