A close look at domain formation in DPPC monolayers

A close look at domain formation in DPPC monolayers
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DOI:
10.1021/la970898e
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发表时间:
1997-12-24
期刊:
影响因子:
3.9
通讯作者:
Vanderlick, TK
Vanderlick, TK
中科院分区:
化学2区
文献类型:
--
作者:
McConlogue, CW;Vanderlick, TK

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二棕榈酰磷脂酰胆碱(DPPC)的不溶性单分子膜表现出相变,导致形成有趣的形状域。我们研究了整个共存区的DPPC畴形状的特征。我们发现,基本的磁畴形状是一个不对称的“豆”与一个扁平的叶和一个明显的空腔。腔是生长的场所,以末端结节或突起的形式生长以形成新的裂片。因此,多叶结构域通过特定的过程从豆类生长;然而,这些结构域并不稳定,并且随着时间的推移会转化回豆类。我们还发现,非典型的压缩方案可以用来产生域的形状,偏离明显的规范,如多叶复合体或环面。
Insoluble monolayers of dipalmitoylphosphatidylcholine (DPPC) exhibit a phase transition resulting in the formation of domains with interesting shapes. We studied the features of DPPC domain shapes throughout the coexistence region. We find that the basic domain shape is an asymmetric "bean" with a flattened lobe and a distinct cavity. The cavity is a locus for growth, in the form of either a terminal nub or a projection which grows to form a new lobe. Multilobed domains thus grow from beans via a specific process; however, these are not stable and transform over time back to beans. We also find that atypical compression schemes can be used to generate domain shapes that stray markedly from the norm, such as multilobed complexes or toruses.