Rosacea pathogenesis, common triggers, and dietary role: The cause, the trigger, and the positive effects of different foods
Rosacea pathogenesis, common triggers, and dietary role: The cause, the trigger, and the positive effects of different foods
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DOI：
10.1016/j.clindermatol.2021.10.004
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发表时间：
2022-03-01
影响因子：
2.7
通讯作者：
Feng, Hao
中科院分区：
文献类型：
--
作者：
Alia, Erisa;Feng, Hao
酒渣鼻是一种常见的慢性炎症性皮肤疾病，主要表现在脸颊、鼻子、下巴和前额，具有典型的复发-缓解过程，主要影响白皙皮肤类型（菲茨帕特里克I和II）。其发病机制尚不清楚，但环境和遗传因素之间复杂的相互作用可能会增强先天免疫反应和神经血管失调。不同的营养物质可能在酒渣鼻的发病机制中发挥作用。许多饮食触发因素，包括热饮料，酒精，辛辣食物，咖啡因，香草，肉桂，烟酸，腌制肉类和乳制品，已被假定为这种疾病;然而，缺乏精心设计和对照研究评估酒渣鼻和饮食因素之间的因果关系。我们已经探索了现有的证据和假设，这些证据和假设基于酒渣鼻的食物分类，皮肤-肠道微生物组轴的作用，以及潜在的有益饮食因素，如益生菌，益生元和高纤维饮食。(C)2021爱思唯尔公司All rights reserved.
Rosacea is a common chronic inflammatory cutaneous disorder, primarily manifesting on the cheeks, nose, chin, and forehead with a classic relapsing-remitting course that affects mostly fair skin types (Fitzpatrick I and II). The pathogenesis remains unclear, but the complex interplay between environmental and genetic factors may augment the innate immune response and neurovascular dysregulation. Different nutrients may play a role in the pathogenesis of rosacea. Many dietary triggers, including hot beverages, alcohol, spicy foods, caffeine, vanilla, cinnamon, niacin, marinated meats, and dairy products, have been postulated for this disease; however, there is a lack of well-designed and controlled studies evaluating the causal relationship between rosacea and dietary factors. We have explored the available evidence and hypotheses based on trigger-food categories of rosacea, the role of the skin-gut microbiome axis, and potentially benefiting dietary factors such as probiotics, prebiotics, and high-fiber diets. (C) 2021 Elsevier Inc. All rights reserved.