HIGH BLOOD-GLUCOSE LEVEL ON HOSPITAL ADMISSION AND POOR NEUROLOGICAL RECOVERY AFTER CARDIAC-ARREST
HIGH BLOOD-GLUCOSE LEVEL ON HOSPITAL ADMISSION AND POOR NEUROLOGICAL RECOVERY AFTER CARDIAC-ARREST
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DOI：
10.1002/ana.410150111
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发表时间：
1984-01-01
影响因子：
11.2
通讯作者：
INUI, TS
中科院分区：
文献类型：
--
作者：
LONGSTRETH, WT;INUI, TS
通过对430例心脏骤停患者院外复苏的回顾性分析，探讨血糖与心脏骤停后神经功能恢复的关系。所有这些患者在入院前均接受了不同量的静脉注射5%葡萄糖溶液。清醒的病人，那些遵循命令或有可理解的语言，被归类为他们是否遭受持续的神经功能缺损。入院时154例未苏醒患者的平均血糖水平高于276例苏醒患者（平均值341 vs 262 mg/100 ml; P < 0.0005）。在276例清醒的患者中，90例有持续性神经功能缺损的患者入院时的平均血糖水平高于186例无神经功能缺损的患者（286 vs. 251 mg/100 ml; P < 0.02）。在排除所有血糖水平> 500 mg/100 ml的患者后，并使用多元回归分析控制潜在混杂变量后，这些显著差异持续存在。
The relationship between blood glucose and neurological recovery after cardiac arrest, was investigated by reviewing the experience of 430 patients resuscitated after out-of-hospital cardiac arrest. All these patients had received variable amounts of i.v. 5% glucose solutions before admission. Awakening patients, those following commands or having comprehensible speech, were classified as to whether they suffered persistent neurological deficits. The mean blood glucose level on hospital admission was higher in 154 patients who never awakened than in 276 who did awaken (mean, 341 vs. 262 mg/100 ml; P < 0.0005). Among the 276 who awakened, 90 patients with persistent neurological deficits had higher mean glucose levels on admission than did 186 without deficits (286 vs. 251 mg/100 ml; P < 0.02). These significant differences persisted after excluding all patients whose glucose levels were > 500 mg/100 ml and after controlling for potentially confounding variables using multiple regression analysis.