Recent fentanyl use among people who inject drugs: Results from a rapid assessment in Baltimore, Maryland
Recent fentanyl use among people who inject drugs: Results from a rapid assessment in Baltimore, Maryland
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DOI：
10.1016/j.drugpo.2019.08.006
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发表时间：
2019-12-01
影响因子：
4.4
通讯作者：
Mehta, Shruti H.
中科院分区：
文献类型：
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作者：
Buresh, Megan;Genberg, Becky L.;Mehta, Shruti H.
背景：在美国，芬太尼相关死亡率持续上升，但对芬太尼使用驱动因素（有意和无意）的了解仍然有限。我们对马里兰州巴尔的摩市当前和以前的注射吸毒者 (PWID) 社区队列进行了快速评估，以了解与芬太尼使用相关的知识、态度和做法。方法：2017 年 11 月至 2018 年 6 月期间，艾滋病相关静脉内经历 (ALIVE) 队列的参与者完成了一项与芬太尼使用相关的调查。使用逻辑回归分析了过去 6 个月内报告吸毒者最近（过去 6 个月）使用芬太尼和偏好芬太尼污染和替代海洛因 (FASH) 的相关性。结果：在 994 名参与者中，28% 的人报告曾经使用过芬太尼，其中 58% 的人报告最近使用过芬太尼。在报告近期（过去 6 个月）吸毒的参与者子集中，近期芬太尼使用的独立相关因素包括年龄较小、男性、无家可归、阿片类药物使用、可卡因使用和每日注射（所有数据均 p < 0.05）。最近使用芬太尼的人中有 18% 报告偏爱 FASH，这与年龄较小、无家可归和每天注射有关（所有人的 p < 0.05）。结论：最近使用芬太尼的情况很常见。减少芬太尼使用相关危害的干预措施应针对年轻、无家可归的吸毒者，他们可能更有可能寻求芬太尼。
Background: Fentanyl-related mortality continues to increase in the US, but knowledge of the drivers of fentanyl use (both intentional and unintentional) remains limited. We conducted a rapid assessment to characterize knowledge, attitudes and practices related to fentanyl use in a community-based cohort of current and former people who inject drugs (PWID) in Baltimore, Maryland.Methods: Between November 2017 and June 2018, participants of the AIDS Linked to the IntraVenous Experience (ALIVE) cohort completed a survey related to fentanyl use. Correlates of recent (past 6 months) fentanyl use and preference for fentanyl-contaminated and-substituted heroin (FASH) were examined using logistic regression among persons who reported using drugs in the prior six months.Results: Of 994 participants, 28% reported ever having used fentanyl, with 58% of those reporting recent use. Independent correlates of recent fentanyl use among the subset of participants reporting recent (past 6 month) drug use were younger age, male sex, homelessness, opioid use, cocaine use, and daily injection (p < 0.05 for all). 18% of those who recently used fentanyl reported preference for FASH, which was associated with younger age, homelessness and daily injection (p < 0.05 for all).Conclusions: Recent fentanyl use was commonly reported. Interventions to reduce the harms associated with fentanyl use should target young, homeless PWID who may be more likely to seek out fentanyl.