Physicochemical and immunochemical characterization of the allergens from the mite Dermatophagoides pteronyssinus.
Physicochemical and immunochemical characterization of the allergens from the mite Dermatophagoides pteronyssinus.
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屋尘螨过敏原的物理化学和免疫化学特征。
DOI：
10.1038/icb.1980.26
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
K. Turner
中科院分区：
文献类型：
--
作者：
G. Stewart;K. Turner
本文描述了翼状棘球绦虫过敏原的物理化学和免疫化学特征，特别是那些指定为Dpt 4和Dpt 12的过敏原。Dpt 4是一种高分子量过敏原，表观分子为274,000道尔顿，pI为4.5。相比之下，抗原性无关的Dpt 12表观分子量为24,000道尔顿，pI为6.6。两种过敏原均表现出分子量或pI的异质性。Dpt 12可能是凤蝶提取物中的主要过敏原，可能与其他工作者先前描述的低分子量过敏原相对应。
The physicochemical and immunochemical characteristics of the allergens from Dermatophagoides pteronyssinus have been described, in particular those for the allergens designated Dpt 4 and Dpt 12. Dpt 4 is a high molecular weight allergen with an apparent molecular of 274,000 daltons and a pI of 4.5. In contrast, the antigenically unrelated Dpt 12 has an apparent molecular weight of 24,000 daltons and a pI 6.6. Both allergens demonstrate heterogeneity, either in molecular weight or pI. Dpt 12 appears to be the major allergen in extracts of D. pteronyssinus and probably corresponds to the low molecular weight allergen previously described by other workers.