A Comparison of Point and Complete Electrode Models in a Finite Difference Model of Invasive Electrode Measurements.
A Comparison of Point and Complete Electrode Models in a Finite Difference Model of Invasive Electrode Measurements.
复制标题
侵入性电极测量的有限差分模型中点电极模型和完整电极模型的比较。
DOI：
10.1109/embc.2018.8513111
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
KWarfield,Simon
中科院分区：
文献类型：
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作者：
EHyde,Damon;Tomas-Fernandez,Xavier;SStone,Scellig;Peters,Jurriaan;KWarfield,Simon
在癫痫手术中，侵入性脑电生理测量通常用于提供所需切除区域的最终验证。这些数据对临床决策至关重要，但由于需要将单个电极测量与特定大脑区域联系起来，这些数据的人工专家分析可能会变得复杂。为了提高对这些数据的源分析，需要精确的生物电模型。考虑到测量位置接近产生皮层源，电组织相互作用的建模对于侵入性测量尤为重要。在这里，我们评估了有限差分完全电极模型对有创皮质电成像铅场计算准确性的影响。我们的研究结果表明，在电极位置附近，使用更简单的点电极模型会产生较大的地形和幅度差异，这可能会影响计算源定位的准确性。
Invasive electrophysiological measurement of brain activity is commonly employed during epilepsy surgery to provide final validation of required resection regions. These data are critical to clinical decision making, but manual expert analysis of these data can be complicated by the need to relate individual electrode measurements to specific brain regions. To improve analysis of these data with source analysis, accurate bioelectric models are needed. Given the proximity of the measurement locations to the generating cortical sources, modeling of electrodetissue interactions is particularly important for invasive measurements. Here, we evaluate the effect of a finite difference complete electrode model on the accuracy of leadfield computations for invasive electrocorticography. Our results show that in the vicinity of electrode locations, use of the simpler point electrode model produces large topographic and magnitude differences that will likely impact the accuracy of computed source localizations.