Virulence factors of Enterococcus faecalis and Enterococcus faecium blood culture isolates
Virulence factors of Enterococcus faecalis and Enterococcus faecium blood culture isolates
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DOI：
10.1007/s100960050007
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发表时间：
2000-01-01
影响因子：
4.5
通讯作者：
Wirth, R
中科院分区：
文献类型：
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作者：
Elsner, HA;Sobottka, I;Wirth, R
对89株粪肠球菌和24株粪肠球菌血培养分离株的已知和潜在毒力因素进行了研究。各因素的患病率分别为（粪肠球菌vs粪肠球菌）：溶血素16% vs 0%，明胶酶55% vs 0%，聚集物63% vs 13%，脂肪酶35% vs 4%，血凝素97% vs 0%。在所有分离物中未检测到脱氧核糖核酸酶。本研究表明血凝素和脂肪酶可能是粪肠球菌的附加毒力因子，而不是粪肠球菌的附加毒力因子，这些因子在肠球菌感染发病机制中的意义有待进一步研究阐明。
Known and potential virulence factors of enterococcal blood culture isolates were studied using 89 Enterococcus faecalis and 24 Enterococcus faecium isolates. The prevalence of the respective factors was (Enterococcus faecalis vs, Enterococcus faecium): hemolysin 16% vs. 0%, gelatinase 55% vs. 0%, aggregation substance 63% vs. 13%, Lipase 35% vs. 4%, hemagglutinin 97% vs. 0%. Deoxyribonuclease was not detected in any isolate. The study showed that hemagglutinin and lipase may represent additional virulence factors of Enterococcus faecalis but not Enterococcus faecium, The significance of these factors in the pathogenesis of enterococcal infection needs to be elucidated in further studies.