Special Meeting Sections for the 7th ASM Conference on Biofilms.
Special Meeting Sections for the 7th ASM Conference on Biofilms.
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第七届 ASM 生物膜会议特别会议部分。
DOI：
10.1128/jb.00565-16
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发表时间：
2016
影响因子：
3.2
通讯作者：
O'Toole,GeorgeA
中科院分区：
文献类型：
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作者：
O'Toole,GeorgeA
2015.这些特别部分包含一个会议概述和九篇研究文章以及四篇小型评论。别忘了看一眼精彩的封面图片。自1996年9月30日至10月4日我作为一名年轻的博士后研究员参加了在犹他州雪鸟举行的第一届ASM生物膜会议以来，生物膜领域的研究已经取得了很大进展。在那次会议上，演讲的重点包括了解这些社区的结构，胞外多糖的组成，以及基质特性如何影响粘附，以及许多成像研究。讨论主题包括“表面化学和/或地形真的影响细菌粘附吗？”以及“所有生物膜都有一个共同的组织吗”其中一些相同的主题延续到2015年的会议，但本期的文章也代表了与这些微生物群落相关的广泛的新主题。例如，包括环状二GMP信号传导、群体感应和进化在生物膜中的作用在内的主题在第一次生物膜会议上没有得到很好的代表（或完全缺席）。在第一次会议上也很难找到遗传或分子研究。事实上，我在那次会议上的海报描述了一个单一的未映射的，生物膜缺陷的突变体，影响游泳运动，这是遗传研究的少数例子之一！当我第一次参加ASM生物膜会议时，我有机会感受到该领域提出的问题。对于一个进入生物膜世界的局外人来说，这种对该领域研究的接触是至关重要的。倾听被调查主题的广度帮助我制定了我对追求感到兴奋的问题，同样重要的是，确定了我不想追求的领域，因为，例如，该子领域已经被调查人员占领了。对于未能参加2015年会议的年轻科学家来说，这一问题将成为目前生物膜领域正在积极研究的问题的一个很好的入口，也许可以让人们定义和完善未来几年要研究的问题。我希望你和我一样喜欢阅读这些特别部分的文章。
2015. These special sections contain a meeting overview and nine research articles as well as four minireviews. And do not forget to take a peek at the terrific cover image. Research in the biofilm field has come a long way since I attended the 1st ASM Conference on Biofilms from 30 September to 4 October 1996 in Snowbird, UT, as a young postdoctoral fellow. At that meeting, the focus of the presentations included understanding the structures of these communities, the composition of the extracellular polysaccharide, and how substratum properties impact adhesion, as well as many imaging studies. The discussion topics included “Do Surface Chemistry and/or Topography Really Affect Bacterial Adhesion?” and “Is There a Common Organization to All Biofilms?” Some of those same themes carry over to the 2015 version of this meeting, but the articles in this issue also represent a broad swath of new themes relevant to these microbial communities. For example, topics including cyclic di-GMP signaling, quorum sensing, and the role of evolution in biofilms were not well-represented (or were completely absent) at the first biofilm conference. And it was difficult to find genetic or molecular studies at the first conference as well. Indeed, my poster at that meeting described a single unmapped, biofilm-defective mutant that impacted swimming motility, and it was one of the few examples of genetic studies!When I attended my first ASM Conference on Biofilms, I had the opportunity to get a feel for the questions being asked in the field. For an outsider coming into the world of biofilms, such exposure to the research in the field was critical. Listening to the breadth of topics under investigation helped me formulate questions I was excited about pursuing and, equally importantly, identify areas I did not want to pursue, because, for example, the subfield was already well occupied with investigators. For young scientists who could not attend the 2015 conference, this issue will serve as an excellent entrée to the questions currently under active investigation in the biofilm field, perhaps letting one define and refine the questions to be investigated in the coming years. I hope you enjoy reading the articles in these special sections as much as I did.