The relationship of psychosocial factors to coronary heart disease in the Framingham study. II. Prevalence of coronary heart disease.
The relationship of psychosocial factors to coronary heart disease in the Framingham study. II. Prevalence of coronary heart disease.
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弗雷明汉研究中心理社会因素与冠心病的关系。
DOI：
10.1093/oxfordjournals.aje.a112557
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发表时间：
1978
影响因子：
5
通讯作者：
W. Kannel
中科院分区：
文献类型：
--
作者：
S. Haynes;M. Feinleib;S. Levine;N. Scotch;W. Kannel
在一项对1822名年龄在45岁至77岁之间的人进行的横断面研究中，评估了20种心理社会量表与冠心病（CHD）患病率的相关性。患有冠心病的女性（45 - 64岁）在A型行为、情绪不稳定、衰老担忧、紧张和愤怒症状量表上的得分显著高于无冠心病的女性。A型行为的职业妇女和家庭主妇冠心病患病率显著高于B型行为。在65岁以下的男性中，A型行为、对衰老的担忧、日常压力和紧张与心肌梗死（MI）的患病率相关。对于65岁以上的男性和女性，婚姻不满意或不和与冠心病的患病率显著相关。在一项多变量分析中，控制了年龄、血压、胆固醇、吸烟和其他心理社会量表。在65岁以下的女性中，弗雷明汉A型行为和情绪不稳定仍然是CHD患病率的重要因素。对衰老的担忧显著区分了65岁以下有MI和无MI的男性。有关的问题进行了讨论，从横截面研究的结果的解释，并提出了四个假设，为今后在这方面的前瞻性工作。
In a cross-sectional study of 1822 persons aged 45 to 77 years of age, the association of 20 psychosocial scales with coronary heart disease (CHD) prevalence was assessed. Women (aged 45 to 64 years) with coronary disease scored significantly higher on the Framingham Type A behavior, emotional lability, aging worries, tension, and anger symptoms scales than women free of CHD. The prevalence of CHD was significantly higher among working women and housewives classified as Type A than as Type B behavior. Among men under 65 years, Framingham Type A behavior, aging worries, daily stress, and tension were associated with the prevalence of myocardial infarction (MI). For men and women over 65 years, marital dissatisfactions or disagreements were significantly related to the prevalence of CHD. In a multivariate analysis, the above associations were controlled for age, blood pressure, cholesterol, smoking, and other psychosocial scales. Among women under 65 years of age, Framingham Type A behavior and emotional lability remained significant discriminators of CHD prevalence. Aging worries significantly differentiated men under 65 with and without MI. Issues related to the interpretation of results from cross-sectional studies are discussed, and four hypotheses are suggested for future prospective work in this area.