HEPATITIS-A - DETECTION BY IMMUNE ELECTRON-MICROSCOPY OF A VIRUSLIKE ANTIGEN ASSOCIATED WITH ACUTE ILLNESS
HEPATITIS-A - DETECTION BY IMMUNE ELECTRON-MICROSCOPY OF A VIRUSLIKE ANTIGEN ASSOCIATED WITH ACUTE ILLNESS
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DOI：
10.1126/science.182.4116.1026
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发表时间：
1973-01-01
期刊：
影响因子：
56.9
通讯作者：
PURCELL, RH
中科院分区：
文献类型：
--
作者：
FEINSTONE, SM;KAPIKIAN, AZ;PURCELL, RH
在甲型肝炎急性期患者的粪便中可见球形27纳米颗粒。该颗粒是这种疾病的血清学特异性的，每个甲型肝炎患者都表现出对这种抗原的血清学反应。这一发现表明，它是甲型肝炎的病原体。
Spherical 27-nanometer particles were visualized in stools obtained from hepatitis A patients in the acute phase of the disease. The particle was serologically specific for this disease, and every hepatitis A patient tested demonstrated a serologic response to this antigen. The findings suggest that it is the etiologic agent of hepatitis A.