THE ASSOCIATION OF HEPATIC APOPROTEIN AND LIPID-METABOLISM IN HAMSTERS AND RATS
THE ASSOCIATION OF HEPATIC APOPROTEIN AND LIPID-METABOLISM IN HAMSTERS AND RATS
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DOI：
10.1016/0300-9629(91)90263-c
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发表时间：
1991-01-01
期刊：
影响因子：
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通讯作者：
REDINGER, RN
中科院分区：
文献类型：
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作者：
LIU, GL;FAN, LM;REDINGER, RN
1. 仓鼠肝脏（而非大鼠肝脏）分泌仅含有脱辅基蛋白 B100 的 VLDL。 脱辅基蛋白B48在仓鼠肠系膜淋巴中被发现，因此血浆脱辅基蛋白B48是肠道来源的。2． 与雄性大鼠相比，雄性仓鼠肝脏分泌的游离胆固醇较少，但分泌的胆固醇酯相似，导致仓鼠的CE/FC比值较高。3． 雄性仓鼠的肝VLDL含有较多的apo B和E，而雌性仓鼠的肝VLDL含有较多的TG和apo A-II/C.4。 喂食高碳饮食的仓鼠会分泌更多的肝脏 VLDL-脱辅基蛋白 B、游离胆固醇酯和胆汁胆固醇。
1. The hamster liver but not that of the rat, secretes VLDL containing only apoprotein B100. Apoprotein B48 was identified in mesenteric lymph of hamsters and therefore plasma apoprotein B48 is of intestinal origin.2. Male hamster livers secrete less free cholesterol but similar cholesterol ester than male rats resulting in a higher CE/FC ratio in hamsters.3. Hepatic VLDL from male hamsters contain more apo B and E while that from females contains more TG and apo A-II/C.4. Hamsters fed high-C diets secrete more hepatic VLDL-apoprotein B, -free and -cholesterol ester, and biliary cholesterol.