Human African trypanosomiasis: current status and eradication efforts.
Human African trypanosomiasis: current status and eradication efforts.
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DOI：
10.1079/pavsnnr202015028
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发表时间：
2020-01-01
期刊：
影响因子：
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通讯作者：
Keeling, Matt J.
中科院分区：
文献类型：
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作者：
Davis, Christopher N.;Rock, Kat S.;Keeling, Matt J.
二十世纪人类非洲锥虫病（HAT）的流行导致数百万人死亡。然而，进入二十一世纪以来，由于投资增加和控制工作的优先顺序，报告的病例数量持续下降。对高危地区进行系统筛查、广泛获得日益先进的诊断和治疗方法，以及大大改善的病媒控制，都有助于在不久的将来实现疾病消除。尽管取得了进展，但 HAT 疾病复发的危险是众所周知的，持续的监测和治疗至关重要。此外，关于 HAT 传播的许多不确定性仍然存在，并且这些不确定性结合起来使得潜在的疾病根除完全未知。
Epidemics of human African trypanosomiasis (HAT) in the twentieth century led to millions of deaths. However, since the start of the twenty-first century, there has been a continued decline in the number of reported cases, due to increased investment and prioritisation of control efforts. Systematic screening of at-risk areas and widespread access to increasingly advanced diagnostics and treatments, along with much improved vector control, has all helped to make disease elimination achievable in the near future. Despite the progress, the danger of disease resurgence is well known for HAT, and continued surveillance and treatment availability are essential. Additionally, many uncertainties regarding HAT transmission remain and combine to make potential disease eradication a complete unknown.