The primary gustatory area in human cerebral cortex studied by magnetoencephalography
The primary gustatory area in human cerebral cortex studied by magnetoencephalography
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DOI：
10.1016/0304-3940(96)12798-1
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发表时间：
1996-07-19
影响因子：
2.5
通讯作者：
Ogawa, H
中科院分区：
文献类型：
--
作者：
Kobayakawa, T;Endo, H;Ogawa, H
用全皮层SQUID系统记录了1 M NaCl和3 mM糖精味觉刺激产生的磁场。MFs的平均起始潜伏期为93 ms的NaCl和172 ms的糖精和水没有得到响应。一个高的相关系数之间的差异的发病MF laveletin在两个tastants和行为反应时间，糖精的反应被延迟或取消后，受试者的舌头与甜味抑制剂的治疗。这一发现表明所获得的MF是由味觉刺激引起的。通过在磁共振图像上绘制估计的电流偶极，我们可以定位初级味觉区在鳃盖和鳃之间的过渡区，如在猕猴中报道的。
Magnetic fields (MFs) from gustatory stimulation with 1 M NaCl and 3 mM saccharin were recorded from the human brain by using a whole-cortex SQUID system. The averaged onset latency of MFs was 93 ms for NaCl and 172 ms for saccharin and no response was obtained for water. A high correlation coefficient was noted between the difference of onset MFs latencies in two tastants and that of behavioral reaction times, and responses to saccharin were delayed or abolished after treatment of a subject's tongue with a sweet-suppressing agent. This finding indicates that the MFs obtained were caused by gustatory stimulation. By plotting the estimated current dipole on the magnetic resonance image, we could locate the primary gustatory area at the transition area between the operculum and insula, as reported in macaque monkeys.