Essential oils and low-intensity electromagnetic pulses in the treatment of androgen-dependent alopecia
Essential oils and low-intensity electromagnetic pulses in the treatment of androgen-dependent alopecia
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DOI：
10.1007/bf02850093
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发表时间：
2003-07-01
影响因子：
3.8
通讯作者：
Roux, ME
中科院分区：
文献类型：
--
作者：
Bureau, JP;Ginouves, P;Roux, ME
这项在健康男性和女性志愿者中进行的双盲随机研究与安慰剂相比，证明了脉冲电磁场与精油联合使用对脱发和头发再生的积极生物学作用，根据26周的常规治疗计划给予。组内的平均毛发计数比较显著有利于治疗组，其显示83%的志愿者的脱发减少，53%的患者的毛发计数比基线增加20%以上。该过程没有表现出任何副作用或不良反应。组织学检查与临床研究相关。平行的免疫组化检查显示增殖指数增加，并且当Ki67（细胞增殖标记物）的表达增加时，在组织学检查中几乎看不到有丝分裂。这种现象的基本原理被认为是由于对静止毛囊的电生理效应。
This double-blind randomized study vs placebo in healthy male and female volunteers demonstrates the positive biologic effect on hair loss and hair regrowth of a pulsed electromagnetic field in combination with essential oils administered according to a regular treatment schedule of 26 weeks. Mean hair count comparisons within the groups significantly favor the treatment group, which exhibited a decrease in hair loss in 83% of the volunteers and a more than 20% hair count increase over baseline in 53% of patients. The process exhibited no side effects or untoward reactions. The histologic examination correlated with the clinical study. A parallel immunohistochemical examination showed an increase in the proliferation index, and when the expression of Ki67 (a cell proliferation marker) is increased, the mitoses are barely visible in the histologic examination. The rationale of this phenomenon is considered to be due to an electrophysiologic effect on the quiescent hair follicle.