Mycobacterium bovis infection in human beings
Mycobacterium bovis infection in human beings
复制标题
DOI：
10.1054/tube.2000.0263
复制
发表时间：
2001-01-01
期刊：
影响因子：
3.2
通讯作者：
Grange, JM
中科院分区：
文献类型：
--
作者：
Grange, JM
牛结核病的病原体牛分枝杆菌也导致一些人类结核病病例。尽管这种形式的人类结核病已被人们认识一个多世纪，但它一直是造成相当大误解和争议的根源。关于结核分枝杆菌和牛分枝杆菌在人类中的相对毒力、感染后人类患病的风险、未发展为疾病的感染的免疫学后果、牛分枝杆菌人际传播的发生以及患病人类对牛的健康风险等问题仍然存在。 HIV/艾滋病大流行的出现提出了免疫抑制对牛分枝杆菌在人与人之间传播的流行病学影响的新问题。尽管在发达国家已基本消灭牛结核病，但在许多发展中国家仍然存在牛结核病，关于其对人类健康影响的流行病学数据很少，但鉴于全世界结核病发病率不断上升，迫切需要这种数据。 (C) 2001 年哈考特出版有限公司。
The causative agent of bovine tuberculosis, Mycobacterium bovis, is also responsible for some cases of tuberculosis in human beings. Although recognized for over a century, this form of human tuberculosis has been a source of considerable misunderstanding and controversy. Questions still remain concerning the relative virulence of M. tuberculosis and M. bovis in human beings, the risk of human disease after infection, the immunological consequences of infection that does not proceed to disease, the occurrence of human-to-human transmission of M, bovis and the health risk of diseased human beings to cattle. The advent of the HIV/AIDS pandemic raises new questions of the epidemiological impact of immunosuppression on the transmission of M. bovis to and between human beings. Although largely eradicated in the developed nations, bovine tuberculosis still occurs in many developing nations and epidemiological data on the impact of this on human health is scanty but, in the light of the increasing incidence of tuberculosis worldwide, it is urgently needed. (C) 2001 Harcourt Publishers Ltd.