Impact of slice thickness on semi-automated measurements for volume and whole-tumor attenuation of colorectal hepatic metastases in multislice computed tomography
Impact of slice thickness on semi-automated measurements for volume and whole-tumor attenuation of colorectal hepatic metastases in multislice computed tomography
复制标题
多层计算机断层扫描中切片厚度对结直肠肝转移瘤体积和全肿瘤衰减半自动测量的影响
DOI：
10.1177/0284185113488579
复制
发表时间：
2013-10
期刊：
影响因子：
--
通讯作者：
曾蒙苏
中科院分区：
文献类型：
--
作者：
饶圣祥;孟滔;张利军;曾蒙苏
背景肿瘤体积和全肿瘤衰减的评估对评估治疗效果有重要价值。目的：评价层厚对结直肠小转移瘤半自动分析（体积、全肿瘤衰减）的影响。材料与方法由两名放射科医生独立地半自动评估1.5、3和5 mm层厚的结直肠肝转移患者的CT数据的体积和全肿瘤衰减。统计学分析包括配对样本t检验和一致性相关系数（CCC）分析，根据最长轴向肿瘤直径（10-20 mm，20-30 mm，30-40 mm）。结果62例患者（男32例，女30例）共62个靶肿瘤。与参考相比，3 mm和5 mm切片厚度的平均体积显著更高（1.5 mm），用于10 mm至20 mm的靶肿瘤（P = 0.0295，CCC = 0.9394; P = 0.0029，CCC = 0.5129（对于5 mm）和5 mm层厚（对于20 mm和30 mm之间的靶肿瘤）（P = 0.0071，CCC = 0.9102）。对于全肿瘤衰减测量，仅在5 mm切片厚度下与10 mm和20 mm之间的靶肿瘤的参考（1.5 mm）相比观察到显著差异（P = 0.0015，CCC = 0.9389）。结论对于10 ~ 20 mm的肝转移瘤，建议采用1.5 mm层厚进行半自动容积测量，而对于全瘤CT衰减，建议层厚不超过3 mm。
Background Volumetric and whole-tumor attenuation assessment of tumor are of value in assessment of treatment. Purpose To assess the impact of slice thickness on semi-automatic analyses (volume, whole-tumor attenuation) for small colorectal hepatic metastases. Material and Methods Computed tomography (CT) data of patients with colorectal hepatic metastases at 1.5-, 3-, and 5-mm slice thickness were semi-automatically evaluated for volume and whole-tumor attenuation by two radiologists independently. Statistical analysis included paired samples t-test and concordance correlation coefficient (CCC) analysis according to the longest axial tumor diameter (10–20 mm, 20–30 mm, 30–40 mm). Results A total of 62 patients (32 men and 30 women) with 62 target tumors were included. The mean volume was significantly higher at 3- and 5-mm slice thicknesses in comparison with the reference (1.5 mm) for the target tumors between 10 mm and 20 mm (P = 0.0295, CCC = 0.9394 for 3 mm; P = 0.0029, CCC = 0.5129 for 5 mm, respectively) and at 5 mm slice thickness for the target tumors between 20 mm and 30 mm (P = 0.0071, CCC = 0.9102). For whole-tumor attenuation measurements, the significant difference was only seen at 5-mm slice thicknesses in comparison with the reference (1.5 mm) for the target tumors between 10 and 20 mm (P = 0.0015, CCC = 0.9389). Conclusion Slice thickness of 1.5 mm might be suggested for semi-automated volumetric measurements, and slice thickness of no more than 3 mm for whole-tumor CT attenuation in hepatic metastasis between 10 mm and 20 mm.
登录
查看更多内容
影响因子：
45.3
作者：
Choi, Haesun;Charnsangavej, Chuslip;Benjamin, Robert S.
通讯作者：
Benjamin, Robert S.
影响因子：
19.7
作者：
Chalian, Hamid;Tochetto, Sandra M.;Yaghmai, Vahid
通讯作者：
Yaghmai, Vahid
DOI：
--
发表时间：
2000
期刊：
Journal of the National Cancer Institute
影响因子：
--
作者：
P. Therasse;S. Arbuck;E. Eisenhauer;J. Wanders;R. Kaplan;L. Rubinstein;J. Verweij;M. V. Van Glabbeke-M.-V.-Van-G
通讯作者：
P. Therasse;S. Arbuck;E. Eisenhauer;J. Wanders;R. Kaplan;L. Rubinstein;J. Verweij;M. V. Van Glabbeke-M.-V.-Van-G
DOI：
10.1055/s-0029-1245983
发表时间：
2011-01
期刊：
RöFo – Fortschritte auf dem Gebiet der Röntgenstrahlen und der Bildgebenden Verfahren
影响因子：
--
作者：
M. Puesken;Boris Buerke;R. Fortkamp;R. Koch;H. Seifarth;Walter Heindel;J. Wessling
通讯作者：
M. Puesken;Boris Buerke;R. Fortkamp;R. Koch;H. Seifarth;Walter Heindel;J. Wessling
影响因子：
3.7
作者：
Kornprat, Peter;Jarnagin, William R.;D'Angelica, Michael
通讯作者：
D'Angelica, Michael