Catecholaminergic inputs to aromatase cells in the canary auditory forebrain
Catecholaminergic inputs to aromatase cells in the canary auditory forebrain
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DOI：
10.1097/01.wnr.0000135920.75925.1e
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发表时间：
2004-08-06
期刊：
影响因子：
1.7
通讯作者：
Balthazart, J
中科院分区：
文献类型：
--
作者：
Appeltants, D;Ball, GF;Balthazart, J
鸣禽的尾侧窝是一个特殊的前脑听觉区域，参与处理物种典型的发声。它接受一个突出的儿茶酚胺能投射，许多纤维在非免疫反应细胞周围形成篮状结构。本研究采用双标免疫细胞化学方法研究了雄性金丝雀尾侧阴毛中酪氨酸羟化酶与类固醇代谢酶（芳香化酶）免疫反应细胞之间的解剖关系。对酪氨酸羟化酶具有免疫反应的纤维与芳香化酶免疫反应细胞建立了许多密切接触，并经常包围这些细胞形成篮状结构。因此，金丝雀尾端绒毛中含有芳香酶的细胞是儿茶酚胺能输入的主要目标。儿茶酚胺能系统和尾部神经酰胺芳香化酶之间的相互作用可能为参与歌曲感知和记忆的雌激素调节提供了一种机制。
The caudomedial nidopallium in songbirds is a specialized forebrain auditory region involved in the processing of species-typical vocalizations. It receives a prominent catecholaminergic projection with many fibers forming basket-like structures around non-immunoreactive cells. We investigated in male canaries the anatomical relationship between tyrosine hydroxylase and cells immunoreactive for the steroid metabolizing enzyme, aromatase, in the caudomedial nidopallium using double-label immunocytochemistry. Fibers immunoreactive for tyrosine hydroxylase established numerous close contacts with aromatase-immunoreactive cells and often encircled these cells to form basket-like structures. Aromatase containing cells in the caudomedial nidopallium are therefore a major target of catecholaminergic inputs in canary. Interactions between catecholaminergic systems and aromatase in the caudomedial nidopallium may provide one mechanism for the regulation of estrogens involved in song perception and memorization.