Foal-related risk factors associated with development of Rhodococcus equi pneumonia on farms with endemic infection
Foal-related risk factors associated with development of Rhodococcus equi pneumonia on farms with endemic infection
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DOI：
10.2460/javma.2003.223.1791
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发表时间：
2003-12-15
期刊：
影响因子：
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通讯作者：
Nevill, M
中科院分区：
文献类型：
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作者：
Chaffin, MK;Cohen, ND;Nevill, M
目的：确定地方性马红球菌感染马场马驹感染马红球菌肺炎的相关危险因素。设计：前瞻性病例对照研究。动物-在2年的时间里，在德克萨斯州的2个马场的220匹马驹。程序-收集的每头马驹的信息包括年龄、分娩前在马场的居住时间、是否有围产期疾病、胎次和先前马驹的健康状况。收集的每匹马驹的信息包括品种、性别、胎龄、出生月份和年份、出生地点、马厩地板和被褥类型、产后管理和预防保健、被动免疫状态、免疫球蛋白的补充、是否去过其他农场或感染马蹄马肺炎的马驹、马厩和牧场暴露、与其他母马驹混合、断奶年龄以及马驹是否患马蹄马肺炎。结果：220匹马驹中32匹（15%）发生马R肺炎，其中4匹（13%）死亡。两个农场中有一个的马驹和研究第二年出生的马驹更有可能患上马乳杆菌肺炎。在多变量分析中，马驹相关因素与马链球菌肺炎的风险无显著相关性。结论和临床相关性结果表明，马驹发生马R肺炎的风险存在农场和年份相关的影响。其他与马驹相关的因素未被确定。
Objective-To identify foal-related risk factors associated with development of Rhodococcus equi pneumonia among foals on farms with endemic R equi infection.Design-Prospective case-control study.Animals-220 foals at 2 equine breeding farms in Texas during a 2-year period.Procedure-Information collected for each dam included age, time housed on the farm prior to parturition, whether there were any peripartum illnesses, parity, and health of previous foals. Information collected for each foal included breed, sex, gestational age, month and year of birth, location of birth, type of flooring and bedding in stall, postpartum management and preventive health care, passive immunity status, supplementation of immunoglobulins, expo sure to other farms or foals affected with R equi pneumonia, stall and pasture exposure, commingling with other mare-foal pairs, age at weaning, and whether the foal developed R equi pneumonia.Results-32 of the 220 (15%) foals developed R equi pneumonia, of which 4 (13%) died. Foals at 1 of the 2 farms and foals born during the second year of the study were more likely to develop R equi pneumonia. Foal-related factors that were examined were not significantly associated with risk of R equi pneumonia in multivariate analyses.Conclusions and Clinical Relevance-Results suggest that there are farm- and year-related effects on the risk that foals will develop R equi pneumonia. Other foal-related factors significantly associated with R equi pneumonia were not identified.