Effectiveness of fluoride in preventing caries in adults
Effectiveness of fluoride in preventing caries in adults
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DOI：
10.1177/154405910708600504
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发表时间：
2007-05-01
影响因子：
7.6
通讯作者：
Huntley, V.
中科院分区：
文献类型：
--
作者：
Griffin, S. O.;Regnier, E.;Huntley, V.
迄今为止，尚未有系统评价发现氟化物可有效预防成人龋齿。这项荟萃分析的目的是检查成人自我和专业应用氟化物和水氟化的有效性。我们使用随机效应模型来估计所有20岁以上成年人和40岁以上成年人的氟化物效应大小（年龋齿增量的绝对差异或相对风险比）。20项研究被纳入最终证据体系。在1980年之后/期间发表的研究中，任何氟化物（自我和专业应用或水氟化）每年避免0.29（95% CI：0.16-0.42）龋冠和0.22（95% CI：0.08-0.37）龋根表面。水氟化的预防分数为27%（95% CI：19%-34%）。这些发现表明，氟化物可以预防所有年龄段的成年人的龋齿。
To date, no systematic reviews have found fluoride to be effective in preventing dental caries in adults. The objective of this meta-analysis was to examine the effectiveness of self- and professionally applied fluoride and water fluoridation among adults. We used a random-effects model to estimate the effect size of fluoride ( absolute difference in annual caries increment or relative risk ratio) for all adults aged 20+ years and for adults aged 40+ years. Twenty studies were included in the final body of evidence. Among studies published after/during 1980, any fluoride ( self- and professionally applied or water fluoridation) annually averted 0.29 ( 95% CI: 0.16-0.42) carious coronal and 0.22 ( 95% CI: 0.08-0.37) carious root surfaces. The prevented fraction for water fluoridation was 27% ( 95% CI: 19%-34%). These findings suggest that fluoride prevents caries among adults of all ages.