Association between family history of diabetes and clusters of adherence to healthy behaviors: cross-sectional results from the Health Examinees-Gem (HFXA-G) study
Association between family history of diabetes and clusters of adherence to healthy behaviors: cross-sectional results from the Health Examinees-Gem (HFXA-G) study
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DOI：
10.1136/bmjopen-2018-025477
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发表时间：
2019-06-01
期刊：
影响因子：
2.9
通讯作者：
Kang, Daehee
中科院分区：
文献类型：
--
作者：
Choi, Jaesung;Choi, Ji-Yeob;Kang, Daehee
研究目的：本研究的设计和背景是一项横断面研究，研究对象是2004-2013年间在韩国39个健康体检中心接受健康体检的受试者。研究对象为128520名健康体检者的基线数据。主要结果和测量结果与坚持规律运动、健康饮食和身体成分的糖尿病家族史之间的关系。结果有糖尿病家族史的受试者更有可能坚持常规运动(男性OR=1.12，95%CI 1.06~1.18，女性OR=1.10，95%CI 1.07~1.14)和健康饮食(OR=1.06，95%CI 1.01~1.12，女性OR=1.06，95%CI 1.01~1.12)，但不太可能有正常的身体成分(OR=0.83，男性95%可信区间0.78~0.87，女性OR=0.83，95%可信区间0.80~0.86)。当受影响的家庭成员是兄弟姐妹、受影响成员的数量增加或受影响成员的确诊年龄低于50岁时，这些联系会得到加强。在男性和女性中，拥有正常的身体成分对确定行为集群很重要，有糖尿病家族史的人不太可能坚持正常的身体成分集群。结论糖尿病高危人群表现出健康的行为，但他们的身体成分并不正常。需要针对综合健康行为的政策和运动，以减轻疾病负担和改善公共卫生。
Objectives This study evaluated whether individuals with affected family member adhered to healthy behaviours.Design and setting This was a cross-sectional study of participants selected from health examinees who underwent the national health check-up programme of Korea in 39 centres between 2004 and 2013.Participants The baseline data of 128 520 participants enrolled in the Health Examinees-Gem study were used for analysis.Main outcomes and measures Associations of family history of diabetes with adherence to regular exercise, healthy diet and body composition, and clusters of healthy behaviours were evaluated while adjusting for potential confounders selected by a directed acyclic graph.Results Participants with a family history of diabetes were more likely to adhere to a regular exercise regimen (OR=1.12, 95% CI 1.06 to 1.18 for men and OR=1.10, 95% CI 1.07 to 1.14 for women) and healthy diet (OR=1.06, 95% CI 1.01 to 1.12 for men and OR=1.06, 95% CI 1.01 to 1.12 for women) but were less likely to have a normal body composition (OR=0.83, 95% CI 0.78 to 0.87 for men and OR=0.83, 95% CI 0.80 to 0.86 for women). These associations were strengthened when the affected family members were siblings, the number of affected members was increased or the age at diagnosis of the affected member was younger than 50 years. In men and women, having a normal body composition is important in determining the cluster of behaviours, and those with a family history of diabetes were less likely to adhere to the normal body composition cluster.Conclusions The group with high risk of diabetes showed healthy behaviors, but they did not have a normal body composition. Policies and campaigns targeting integrated health behaviors will be needed to reduce the burden of diseases and improve public health.