Joint association of magnesium and iron intake with anemia among Chinese adults
Joint association of magnesium and iron intake with anemia among Chinese adults
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DOI：
10.1016/j.nut.2008.05.002
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发表时间：
2008-10-01
期刊：
影响因子：
4.4
通讯作者：
Garg, Manohar
中科院分区：
文献类型：
--
作者：
Shi, Zumin;Hu, Xiaoshu;Garg, Manohar
目的：炎症和缺铁是引起贫血的两个重要原因。镁摄入量与炎症呈负相关。然而，很少有人知道镁摄入量是否与贫血有关。我们评估了镁和铁的摄入量与贫血的联合协会在中国adultes.Methods：2849名男性和女性20岁以上的年龄在2002年进行了横断面家庭调查。营养素的摄入量进行了评估的3-d称重食物记录。结果：贫血患病率男性为18.3%，女性为31.5%。镁和铁的摄入量与血红蛋白水平呈正相关，与贫血的患病率呈负相关。调整潜在混杂因素后，第四个四分位数与第一个四分位数相比，铁和镁摄入量分别使贫血风险降低26%（趋势P = 0.03）和52%（P < 0.01）。在镁和铁摄入量最高的参与者中观察到贫血的风险最低（比值比0.46，95%置信区间0.31-0.68）。铁摄入量和贫血的负相关，但镁摄入量和贫血的协会被修改的血清铁蛋白水平。所观察到的关系没有明显修改gender.Conclusion：这项研究表明，镁是一个有效的预测中国成年人贫血。(C)2008年爱思唯尔公司All rights reserved.
Objective: Inflammation and iron deficiency are two important causes of anemia. Magnesium intake is inversely associated with inflammation. However, little is known as to whether magnesium intake is related to anemia. We assessed the joint association of magnesium and iron intake with anemia among Chinese adults.Methods: A cross-sectional household survey of 2849 men and women 20 y of age or older was conducted in 2002. Nutrient intakes were assessed by 3-d weighed food records. Serum ferritin and hemoglobin concentrations were measured.Results: The prevalence of anemia was 18.3% in men and 31.5% in women. Magnesium and iron intakes were positively associated with hemoglobin levels and inversely related to the prevalence of anemia. The risks of anemia were reduced by 26% (P for trend = 0.03) and 52% (P < 0.01), respectively, for iron and magnesium intake comparing the fourth quartile with the first with adjustment for potential confounders. The lowest risk of anemia was observed among participants with the highest intakes of magnesium and iron (odds ratio 0.46, 95% confidence interval 0.31-0.68). The inverse association of iron intake and anemia but not the association of magnesium intake and anemia was modified by serum ferritin levels. The observed relations were not appreciably modified by gender.Conclusion: This study suggests that magnesium is a potent predictor of anemia in Chinese adults. (C) 2008 Elsevier Inc. All rights reserved.