Behavioural effects of ablation of the pigeon-equivalent of the mammalian prefrontal cortex
Behavioural effects of ablation of the pigeon-equivalent of the mammalian prefrontal cortex
复制标题
哺乳动物前额皮质的鸽子等效物消融的行为影响
DOI：
10.1016/0166-4328(93)90012-f
复制
发表时间：
1993
影响因子：
2.7
通讯作者：
I. Divac
中科院分区：
文献类型：
--
作者：
J. Mogensen;I. Divac
六只鸽子接受了延迟交替和亮度辨别训练。其中三人接受了后背外侧新纹状体（PDLNS）的消融，据信该纹状体对应于哺乳动物的前额叶皮层。其他三只鸽子的纹状体上损伤是通过局部注射鹅膏酸诱导的。 PDLNS 消融对延迟交替性能的损害比纹状体上病变的影响更大。在亮度辨别方面，仅在术后第一次疗程中且仅在 PDLNS 组中出现轻度损伤。我们得出的结论是，鸽子 PDLNS 的消融和哺乳动物前额叶皮层的消融也会引起类似的损伤。因此，前额叶皮层似乎不是哺乳动物的特权，但可能以不同的结构变体出现在所有“高等”脊椎动物中。
Six pigeons were trained to perform delayed alternation and brightness discrimination. Three of them underwent ablation of the posterodorsolateral neostriatum (PDLNS) which is believed to correspond to the mammalian prefrontal cortex. In the other three pigeons hyperstriatal lesions were induced by local injections of ibotenic acid. Ablation of PDLNS impaired performance of delayed alternation much more than did the hyperstriatal lesion. In brightness discrimination, a mild impairment occurred only on the first postoperative session and only in the PDLNS group. We conclude that the ablation of PDLNS in pigeons and of the prefrontal cortex in mammals induce similar impairments. Thus, the prefrontal cortex appears not to be a privilege of mammals, but may appear in different architectonic variants in all “higher” vertebrates.