Model Formulation: Translating Clinical Informatics Interventions into Routine Clinical Care: How Can the RE-AIM Framework Help?

Model Formulation: Translating Clinical Informatics Interventions into Routine Clinical Care: How Can the RE-AIM Framework Help?
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模型制定:将临床信息学干预转化为常规临床护理:RE-AIM 框架有何帮助?

DOI:
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发表时间:
2009
期刊:
J. Am. Medical Informatics Assoc.
影响因子:
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通讯作者:
C. Ruland
C. Ruland
中科院分区:
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文献类型:
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作者:
S. Bakken;C. Ruland

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OBJECTIVE Clinical informatics intervention research suffers from a lack of attention to external validity in study design, implementation, evaluation, and reporting. This hampers the ability of others to assess the fit of a clinical informatics intervention with demonstrated efficacy in one setting for implementation in their setting. The objective of this model formulation paper is to demonstrate the applicability of the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework with proposed extensions to clinical informatics intervention research and describe the framework's role in facilitating the translation of evidence into practice and generation of evidence from practice. Both aspects are essential to reap the clinical and public health benefits of clinical informatics research. DESIGN We expanded RE-AIM through the addition of assessment questions relevant to clinical informatics intervention research including those related to predisposing, enabling, and reinforcing factors and validated it with two case studies. RESULTS The first case study supported the applicability of RE-AIM to inform real world implementation of a clinical informatics intervention with demonstrated efficacy in randomized controlled trials (RCTs)--the Choice (Creating better Health Outcomes by Improving Communication about Patients' Experiences) intervention. The second, an RCT of a personal digital assistant-based decision support system for guideline-based care, illustrated how RE-AIM can be used to inform the design of an efficacy RCT that captures essential contextual details typically lacking in RCT design and reporting. CONCLUSION The case studies validate, through example, the applicability of RE-AIM to inform the design, implementation, evaluation, and reporting of clinical informatics intervention studies.