Nextstrain: real-time tracking of pathogen evolution
Nextstrain: real-time tracking of pathogen evolution
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DOI：
10.1093/bioinformatics/bty407
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发表时间：
2018-12-01
期刊：
影响因子：
5.8
通讯作者：
Neher, Richard A.
中科院分区：
文献类型：
--
作者：
Hadfield, James;Megill, Colin;Neher, Richard A.
了解病原体的传播和演变对于有效的公共卫生措施和监测非常重要。Nextstrain由病毒基因组数据库、用于病毒动力学分析的生物信息学管道和交互式可视化平台组成。这些共同提供了对一系列具有高度公共卫生重要性的病毒病原体的演变和传播的实时视图。可视化将序列数据与其他数据类型（如地理信息、血清学或宿主物种）整合在一起。Nextstrain将我们目前的理解汇编到一个单一的可访问位置，向卫生专业人员，流行病学家，病毒学家和公众开放。
Understanding the spread and evolution of pathogens is important for effective public health measures and surveillance. Nextstrain consists of a database of viral genomes, a bioinformatics pipeline for phylodynamics analysis, and an interactive visualization platform. Together these present a real-time view into the evolution and spread of a range of viral pathogens of high public health importance. The visualization integrates sequence data with other data types such as geographic information, serology, or host species. Nextstrain compiles our current understanding into a single accessible location, open to health professionals, epidemiologists, virologists and the public alike.