Wavelength Specificity of Photoparoxysmal Responses in Idiopathic Generalized Epilepsy
Wavelength Specificity of Photoparoxysmal Responses in Idiopathic Generalized Epilepsy
复制标题
特发性全身性癫痫光阵发性反应的波长特异性
DOI：
10.1111/j.1528-1157.1995.tb00466.x
复制
发表时间：
1995
期刊：
影响因子：
5.6
通讯作者：
M. Seino
中科院分区：
文献类型：
--
作者：
Y. Takahashi;T. Fujiwara;K. Yagi;M. Seino
摘要：利用光学滤光片，我们分析了特发性全面性癫痫(ICE)光敏性患者光性阵发性反应(PPR)的波长特异性。我们指定PPR700 nm(660720 Nm)波长光谱是在一些正常三原色患者中引起∼反应所必需的唯一可见光谱，并表明任何包含这一基本波长光谱的闪光都可以引起PPR，而不依赖于受刺激的锥体的数目。滤光片对700 nm波长光谱的吸收消除了正常三色ICE患者的PPR。在一名患有Deurant畸形的IGE患者中，包含580至700 nm部分波长光谱的间歇性闪光会引发PPR。这些数据对PPR的波长特异性提出了一种新的解释：在一些光敏性ICE患者中，包含不会在视网膜神经节细胞水平产生拮抗锥体相互作用的波长光谱的闪光可以引发PPR。
Summary: Using optic filters, we analyzed the wavelength specificity of photoparoxysmal responses (PPR) in photosensitive patients with idiopathic generalized epilepsy (ICE). We specified the wavelength spectrum ∼700 nm (660–720 nm) as the only visible spectrum essential for eliciting PPR in some normal trichromat IGE patients and showed that any flashing lights containing this essential wavelength spectrum could elicit PPR independent of the number of stimulated cones. Absorption of the wavelength spectrum ‐700 nm by optic filters eliminated PPR in normal trichromat ICE patients. In an IGE patient with deuteranomaly, intermittent flashing lights containing a part of the wavelength spectrum from 580 to 700 nm elicited PPR. These data suggest a new interpretation of wavelength specificity of PPR: Flashing lights containing the wavelength spectrum that does not produce antagonistic cone interactions at the level of retinal ganglion cells can elicit PPR in some photosensitive ICE patients.