Field immobilisation of southern elephant seals with intravenous tiletamine and zolazepam
Field immobilisation of southern elephant seals with intravenous tiletamine and zolazepam
复制标题
静脉注射替来他明和唑拉西泮对南象海豹进行现场固定
DOI：
10.1136/vr.146.9.251
复制
发表时间：
2000
影响因子：
2.2
通讯作者：
M. Bester
中科院分区：
文献类型：
--
作者：
C. McMahon;C. McMahon;H. Burton;S. McLean;D. Slip;M. Bester
以0.46(0.08)毫克/公斤的平均剂量率(SD)静脉注射替利他明和唑拉西潘的混合物，以固定南部象海豹(Mirougo Leonina)。该剂量麻醉效果满意，无副作用，诱导时间短，持续时间短，恢复时间短。平均(SD)诱导时间为26(9)秒，平均麻醉水平为4.4个单位(8分制)。与雌性海豹相比，雄性海豹服用的药物更少，保持静止的时间更短，恢复得更快。男性平均剂量为0.44(0.06)mg/kg，女性为0.48(0.08)mg/kg，持续时间分别为14.9(4.5)分钟和16.1(5.3)分钟。男性从静止状态恢复的平均时间为14.5分钟(4.6)，女性为15.7分钟(5.3)。生理条件和大小对麻醉持续时间有显著影响。较薄的海豹保持不动18(7)分钟，而较胖的海豹保持不动15(4)分钟(P<；0.0001)。
Southern elephant seals (Miroungo leonina) were immobilised with a mixture of tiletamine and zolazepam administered intravenously at a mean (sd) dose rate of 0.46 (0.08) mg/kg. This dose provided a satisfactory degree of anaesthesia with no side effects, and the induction, duration and recovery times were short. The mean (sd) induction time was 26 (9) seconds and the mean level of anaesthesia was 4.4 units on an eight-point scale. Male seals were given less drug than female seals, remained immobilised for shorter periods and recovered sooner. The mean (sd) dose of drug administered to males was 0.44 (0.06) mg/kg and to females 0.48 (0.08) mg/kg, and the mean (sd) duration times were 14.9 (4.5) minutes and 16.1 (5.3) minutes. The mean (sd) time taken to recover from immobilisation was 14.5 (4.6) minutes for males and 15.7 (5.3) minutes for females. Physiological condition and size significantly affected the duration of anaesthesia. Thin seals remained immobilised for 18 (7) minutes whereas fatter seals remained immobilised for 15 (4) minutes (P<0.0001).