Comparison of the effects of flaxseed oil and sunflower seed oil consumption on serum glucose, lipid profile, blood pressure, and lipid peroxidation in patients with metabolic syndrome
Comparison of the effects of flaxseed oil and sunflower seed oil consumption on serum glucose, lipid profile, blood pressure, and lipid peroxidation in patients with metabolic syndrome
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DOI：
10.1016/j.jacl.2017.11.004
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发表时间：
2018-02-01
影响因子：
4.4
通讯作者：
Yarmohammadi, Hassan
中科院分区：
文献类型：
--
作者：
Akrami, Atefeh;Nikaein, Farzad;Yarmohammadi, Hassan
背景：代谢综合征（MetSyn）增加了II型糖尿病的风险以及心血管疾病的发病率和死亡率。亚麻籽油（Flaxseedoil，FO）是人体必需的ω-3脂肪酸的主要植物来源之一。目的：本研究的目的是比较消费的FO和向日葵籽油（SO）对脂质过氧化和其他症状的MetSyn.METHODS：这项随机对照干预试验进行了60名志愿者，年龄在30至60岁，谁被诊断为MetSyn在设拉子，伊朗。符合入选标准的受试者采用区组随机化方法被随机分配到SO组（n = 30，接受25 mL/d SO）和FO组（n = 30，接受25 mL/d FO）。所有参与者的饮食都是相同的。分别于治疗前及治疗7周末测定血压、血脂、空腹血糖、丙二醛。结果：治疗7周末，两组患者血脂、空腹血糖水平无显著性差异。然而，在用FO和SO治疗后，在各组中观察到总胆固醇、低密度脂蛋白胆固醇（FO为5.6%，SO为10.8%）和甘油三酯水平的显著降低（P <0.05）。尽管如此，组间变化是显著的（
BACKGROUND: Metabolic syndrome (MetSyn) increases the risk of type II diabetes and morbidity and mortality due to cardiovascular diseases. Flaxseed oil (FO), as a functional food, is one of the major vegetal sources of essential omega-3 fatty acids. OBJECTIVE: This study aimed to compare the effects of consumption of FO and sunflower seed oil (SO) on lipid peroxidation and other symptoms of MetSyn.METHODS: This randomized controlled interventional trial was conducted on 60 volunteers aged 30 to 60 years who were diagnosed with MetSyn in Shiraz, Iran. The participants who fulfilled the inclusion criteria were randomly assigned to SO (n = 30, receiving 25 mL/d SO) and FO (n = 30, receiving 25 ml/d FO) groups using block randomization. The diets were identical for all the participants. Blood pressure (BP), serum lipid, fasting blood sugar, and malondialdehyde were measured at baseline and at the end of week 7.RESULT: The results showed no significant difference between the 2 groups regarding blood lipid levels and fasting blood sugar at the end of the study. However, significant reductions in total cholesterol, low-density lipoprotein cholesterol (5.6% in FO and 10.8% in SO), and triglyceride levels were seen within each group after treatment with FO and SO (P < .05). Nonetheless, between-group changes were significant (