Sedentary behavior, physical activity, and markers of health in older adults.
Sedentary behavior, physical activity, and markers of health in older adults.
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DOI：
10.1249/mss.0b013e318288a1e5
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发表时间：
2013-08
影响因子：
4.1
通讯作者：
Colbert LH
中科院分区：
文献类型：
--
作者：
Gennuso KP;Gangnon RE;Matthews CE;Thraen-Borowski KM;Colbert LH
通过中等强度的体力活动(MVPA)水平来检验久坐行为(SB)、心脏代谢危险因素和自我报告的身体功能之间的联系。横断面分析来自2003年至2006年美国国家健康和营养检查调查(NHANES)，调查对象为1914名65岁的≥老年人。MVPA和SB来源于佩戴一周的Actigraph加速计。MVPA被归类为足以满足当前美国指南(≥150分钟/周)或不足以满足；SB被分成四分位数。在实验室分析和体检中检查了各种生物标记物，并自行报告了功能限制的数量。主要分析SB和MVPA在生物标志物关联上的统计交互作用，然后通过相关的协变量调整来检验它们的独立关联。SB平均为9.4±2.3小时/天(Mean±SD)，约35%被归类为足够活跃。总体而言，SB和MVPA之间没有发现任何有意义的统计学交互作用；然而，在调整MVPA后，SB与体重(p<；0.01)、BMI(p<；0.01)、腰围(p<；0.01)、C反应蛋白(CRP)(p<；0.01)、血糖(p=0.04)和功能受限(p<；0.01)之间存在强烈的独立正相关。同样，MVPA与体重(p=0.01)、BMI(p<；0.01)、腰围(p<；0.01)、舒张压(p=0.04)、C反应蛋白(p<；0.01)、经SB校正后的功能障碍数(p<；0.01)呈负相关。结果表明，在当前样本中，充足的MVPA并没有改善SB与心脏代谢危险因素或功能限制之间的负关联，并且它们与所检查的结果之间的关联在乘性尺度上是独立的。因此，老年人可以从联合处方中受益，积累足够的MVPA，避免长时间坐着。
To examine the association between sedentary behavior (SB), cardiometabolic risk factors, and self-reported physical function by level of moderate-vigorous physical activity (MVPA). Cross-sectional analysis was completed on 1, 914 older adults aged ≥65 years from the 2003–2006 U.S. National Health and Nutrition Examination Survey (NHANES). MVPA and SB were derived from Actigraph accelerometers worn for one week. MVPA was categorized as sufficient to meet the current U.S. guidelines (≥150 minutes/week) or not; SB was split into quartiles. Various biomarkers were examined in laboratory analyses and physical exams, and the number of functional limitations was self-reported. Statistical interaction between SB and MVPA on the biomarker associations was the primary analysis, followed by an examination of their independent associations with relevant covariate adjustment. Average SB was 9.4±2.3 hours/day (mean ± SD) and approximately 35% were classified as sufficiently active. Overall, no significant meaningful statistical interactions were found between SB and MVPA for any of the outcomes; however, strong independent positive associations were found between SB and weight (p<0.01), BMI (p<0.01), waist circumference (p<0.01), C-reactive protein (CRP) (p<0.01), plasma glucose (p=0.04), and number of functional limitations (p<0.01) after adjustment for MVPA. Similarly, MVPA was negatively associated with weight (p=0.01), BMI (p<0.01), waist circumference (p<0.01), diastolic blood pressure (p=0.04), CRP (p<0.01), and number of functional limitations (p<0.01) after adjustment for SB. The results suggest that sufficient MVPA did not ameliorate the negative associations between SB and cardiometabolic risk factors or functional limitations in the current sample and that there was independence on a multiplicative scale in their associations with the outcomes examined. Thus, older adults may benefit from the joint prescription to accumulate adequate MVPA and avoid prolonged sitting.