Inversions shape the divergence of Drosophila pseudoobscura and Drosophila persimilis on multiple timescales
Inversions shape the divergence of Drosophila pseudoobscura and Drosophila persimilis on multiple timescales
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DOI：
10.1111/evo.14278
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发表时间：
2021-05
期刊：
影响因子：
3.3
通讯作者：
Katharine L Korunes;C. A. Machado;M. Noor
中科院分区：
文献类型：
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作者：
Katharine L Korunes;C. A. Machado;M. Noor
通过形成减数分裂重组，染色体倒位可以影响杂交物种之间的遗传交换。尽管人们认识到倒转在分化和物种形成等进化过程中的重要性，但随着时间的推移，梳理倒转的影响仍然具有挑战性。例如，它们对序列分歧的影响主要是通过创建连锁不平衡预物种形成块还是通过阻止物种形成后的基因流动而产生？我们全面研究了经典系统（果蝇伪暗果蝇和果蝇）整个进化史上倒位对基因流的影响。我们使用广泛的全基因组序列数据来报告染色体排列的渗入和分歧模式。总体而言，我们发现证据表明，倒转在三个不同的时间尺度上导致了 D. pseudoobscura 和 D. persimilis 之间的分化模式：（1）在物种形成过程早期祖先多态性的分离，（2）在 D. pseudoobscura 和 D. persimilis 分裂之后，但在 D. pseudoobscura 亚种分裂之前的基因流，以及（3）最近在同域 D. pseudoobscura 和 D. pseudoobscura 之间的基因流D. persimilis，D.pseudoobscura 亚种分裂后。我们根据我们对这个经典系统进化的理解来讨论这些结果，并为解释其他系统中的分歧度量提供注意事项。
By shaping meiotic recombination, chromosomal inversions can influence genetic exchange between hybridizing species. Despite the recognized importance of inversions in evolutionary processes such as divergence and speciation, teasing apart the effects of inversions over time remains challenging. For example, are their effects on sequence divergence primarily generated through creating blocks of linkage disequilibrium prespeciation or through preventing gene flux after speciation? We provide a comprehensive look into the influence of inversions on gene flow throughout the evolutionary history of a classic system: Drosophila pseudoobscura and Drosophila persimilis. We use extensive whole‐genome sequence data to report patterns of introgression and divergence with respect to chromosomal arrangements. Overall, we find evidence that inversions have contributed to divergence patterns between D. pseudoobscura and D. persimilis over three distinct timescales: (1) segregation of ancestral polymorphism early in the speciation process, (2) gene flow after the split of D. pseudoobscura and D. persimilis, but prior to the split of D. pseudoobscura subspecies, and (3) recent gene flow between sympatric D. pseudoobscura and D. persimilis, after the split of D. pseudoobscura subspecies. We discuss these results in terms of our understanding of evolution in this classic system and provide cautions for interpreting divergence measures in other systems.