DERMATOMYOSITIS AND MALIGNANCY - A MULTICENTER COOPERATIVE STUDY
DERMATOMYOSITIS AND MALIGNANCY - A MULTICENTER COOPERATIVE STUDY
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DOI：
10.1159/000248032
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发表时间：
1990-01-01
期刊：
影响因子：
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通讯作者：
FAYOL, J
中科院分区：
文献类型：
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作者：
BONNETBLANC, JM;BERNARD, P;FAYOL, J
回顾性分析了22个皮肤科5年来118例皮肌炎（DM）病例。34例（28%）与糖尿病发生1年前（7例）、合并（22例）或发生1年后（5例）诊断的癌症相关。只有8例（22%）糖尿病的发展与癌症的副肿瘤发展有明确的相关性。在大多数情况下，不需要广泛的诊断程序来识别肿瘤。58%的癌症相关性糖尿病患者在诊断为糖尿病后20（8-29）个月死亡。这项基于短时间的多中心研究证实并扩展了之前基于回顾性单中心分析的观察结果。
A retrospective analysis of 118 cases of dermatomyositis (DM) collected in 22 departments of dermatology over a 5-year period is presented. 34 cases (28%) were associated with a cancer that was diagnosed more than 1 year prior to (7 cases), concomitantly (22 cases) or more than 1 year after (5 cases) the occurrence of DM. There was a clear correlation between the evolution of DM and a cancer paraneoplastic evolution in 8 cases only (22%). In most of the cases, no extensive diagnostic procedures were necessary for identifying the tumors. 58% of the patients with cancer-associated DM died 20 (8-29) months after the diagnosis of DM. This multicenter study based on a short period of time confirms and extends previous observations based on retrospective single-center analyses.