Heart rate variability in human immunodeficiency virus-positive individuals
Heart rate variability in human immunodeficiency virus-positive individuals
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DOI：
10.1016/j.ijcard.2003.02.002
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发表时间：
2004-03-01
影响因子：
3.5
通讯作者：
Deepak, KK
中科院分区：
文献类型：
--
作者：
Mittal, CM;Wig, N;Deepak, KK
背景：心率变异性（HRV）是心脏自主神经张力的标志。据报道，艾滋病患者的心率变异性降低。我们进行这项研究，以了解是否HRV是压抑的人类免疫缺陷病毒（HIV）阳性的个人没有艾滋病。研究方法：我们前瞻性研究了21例HIV阳性（33+/-11岁）和18例健康志愿者（31+/-9岁）的短期心电图（ECG）监测频谱分析的HRV。所有艾滋病毒阳性者都没有任何自主神经功能障碍或心脏功能障碍的临床证据。还对HIV血清阳性患者进行了超声心动图检查，以排除左心室（LV）收缩功能障碍。所有这些人都没有任何艾滋病的证据。结果：平均CD 4+淋巴细胞计数为426+/-166/mm3。HIV患者的射血分数（EF%）为62.4+/-6.4。HIV阳性者HRV总功率显著降低（p
Background: Heart rate variability (HRV) is a marker of cardiac autonomic tone. Depressed HRV has been reported in patients with AIDS. We conducted this study to find out if HRV is depressed in human immunodeficiency virus (HIV)-positive individuals without AIDS. Methods: We studied prospectively HRV by spectral analysis of short-term electrocardiography (ECG) monitoring in 21 HIV-positives (33+/-11 years) and in 18 healthy volunteers (31+/-9 years). None of the HIV-positives had any clinical evidence of autonomic or cardiac dysfunction. Echocardiography was also performed in HIV-seropositives to rule out left ventricular (LV) systolic dysfunction. All these individuals did not have any evidence of AIDS. Results: Mean CD4+ lymphocyte count was 426+/-166/mm(3). The ejection fraction (EF%) of HIV patients was 62.4+/-6.4. The total power of HRV was reduced significantly in HIV-positive individuals (p