Bonobos Fall within the Genomic Variation of Chimpanzees
Bonobos Fall within the Genomic Variation of Chimpanzees
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DOI：
10.1371/journal.pone.0021605
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发表时间：
2011-06-29
期刊：
影响因子：
3.7
通讯作者：
Paeaebo, Svante
中科院分区：
文献类型：
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作者：
Fischer, Anne;Pruefer, Kay;Paeaebo, Svante
为了深入了解黑猩猩和黑猩猩内部和之间的遗传变异和进化关系的模式，我们对分布在15个常染色体区域的150,000个碱基对的核DNA以及20个黑猩猩和58个黑猩猩的完整线粒体基因组进行了测序。除了西部黑猩猩，我们发现黑猩猩基于样本位置的遗传分离很差。相比之下，在许多地区，矮黑猩猩总是聚集在一起，但作为一个群体属于黑猩猩的变异范围。因此，虽然黑猩猩保留了早于矮黑猩猩物种形成的基因组变异，但在矮黑猩猩内部发生了广泛的谱系分类，以至于它们的大部分基因组可以追溯到单一的共同祖先，这一祖先可以追溯到他们作为一个独立于黑猩猩的群体的起源。
To gain insight into the patterns of genetic variation and evolutionary relationships within and between bonobos and chimpanzees, we sequenced 150,000 base pairs of nuclear DNA divided among 15 autosomal regions as well as the complete mitochondrial genomes from 20 bonobos and 58 chimpanzees. Except for western chimpanzees, we found poor genetic separation of chimpanzees based on sample locality. In contrast, bonobos consistently cluster together but fall as a group within the variation of chimpanzees for many of the regions. Thus, while chimpanzees retain genomic variation that predates bonobo-chimpanzee speciation, extensive lineage sorting has occurred within bonobos such that much of their genome traces its ancestry back to a single common ancestor that postdates their origin as a group separate from chimpanzees.