Digging for Buried Amino Acids Unearths New Protein Quality Control Treasure.

Digging for Buried Amino Acids Unearths New Protein Quality Control Treasure.
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挖掘埋藏的氨基酸发现了新的蛋白质质量控​​制宝藏。

DOI:
10.1016/j.str.2015.06.008
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发表时间:
2015
期刊:
Structure (London, England : 1993)
影响因子:
--
通讯作者:
Gardner,RichardG
Gardner,RichardG
中科院分区:
--
文献类型:
--
作者:
Jones,RamonD;Gardner,RichardG

文献摘要

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蛋白质的功能依赖于三维结构,但许多蛋白质的稳定性较差,容易发生错误折叠。在本期《结构》中,布洛克等人。 (2015) 提出了一种新颖的计算建模方法来深入了解蛋白质稳定性和错误折叠。
Proteins rely on three-dimensional structure for function, yet many proteins are marginally stable and prone to misfolding. In this issue ofStructure, Brock et al. (2015) present a novel computational modeling method to gain insights into protein stability and misfolding.