ACNE-VULGARIS IN EARLY ADOLESCENT BOYS - CORRELATIONS WITH PUBERTAL MATURATION AND AGE
ACNE-VULGARIS IN EARLY ADOLESCENT BOYS - CORRELATIONS WITH PUBERTAL MATURATION AND AGE
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DOI：
10.1001/archderm.127.2.210
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发表时间：
1991-02-01
影响因子：
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通讯作者：
ELDER, N
中科院分区：
文献类型：
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作者：
LUCKY, AW;BIRO, FM;ELDER, N
为了评估青春期男孩寻常痤疮的患病率和严重程度，我们研究了俄亥俄州辛辛那提的219名黑人和249名白色男孩，他们都是五年级到九年级的学生。 平均年龄为12.2 ± 1.4岁，范围为9至15岁。 青春期成熟评分为坦纳阴毛阶段（PH I至V）和青春期阶段（PS I至IV），包括睾丸体积评估。 根据粉刺（开放性加闭合性粉刺）和炎性（丘疹加脓疱）病变的数量对痤疮进行评分。 分别分析粉刺和炎性病变，并以数值评分和等级（1，小于或等于病变; 2，11 - 25个病变; 3，大于或等于26个病变）进行评价。 2级和3级被认为是具有临床意义的痤疮。 痤疮变得越来越严重的推进成熟。 平均痤疮评分与PS和阴毛的相关性好于与年龄的相关性。 黑人受试者比白色受试者更成熟。 PS I和II的黑人男孩比白色男孩有更多的粉刺; PS I和III的白色男孩有更多的炎性病变。 PS I中已经存在临床显著的粉刺性痤疮，PS IV中100%的男孩发生粉刺性痤疮。 相比之下，PS I组没有男孩，PS IV组只有50%的男孩有明显的炎性痤疮。 面中部痤疮为主。 我们的结论是痤疮的患病率和严重程度与青春期男孩的青春期成熟有关。 粉刺性痤疮比炎症性疾病更常见、更严重。 认识到青春期前和青少年痤疮的程度和严重性，最终可能提供早期干预的理由，从而预防严重的寻常痤疮。
To assess the prevalence and severity of acne vulgaris in young adolescent boys, we studied 219 black and 249 white boys in fifth through ninth grades in Cincinnati, Ohio. The mean age was 12.2 +/- 1.4 years, with a range of 9 to 15 years. Pubertal maturation was scored as Tanner pubic hair stages (PH I to V) and pubertal stages (PS I to IV) that included testicular volume assessment. Acne was scored by number of comedonal (open plus closed comedones) and inflammatory (papules plus pustules) lesions. Comedonal and inflammatory lesions were analyzed separately and evaluated both as numerical scores and as grades (1, less-than-or-equal-to lesions; 2, 11 to 25 lesions; and 3, greater-than-or-equal-to 26 lesions). Grades 2 and 3 were considered clinically significant acne. Acne became progressively more severe with advancing maturity. Mean acne scores correlated better with PS and pubic hair than with age. Black subjects were more mature than white subjects. Black boys in PS I and II had significantly more comedones than white boys; white boys had significantly more inflammatory lesions at PS I and III. Clinically significant comedonal acne was already present in PS I and occurred in 100% of boys in PS IV. In contrast, no boys at PS I and only 50% at PS IV had significant inflammatory acne. Midfacial acne dominated. We concluded that acne prevalence and severity correlate well with advancing pubertal maturation in young adolescent boys. Comedonal acne was more frequent and severe than inflammatory disease. Awareness of the extent and severity of acne in preadolescents and young adolescents may ultimately provide rationale for early intervention and thus prevention of severe acne vulgaris.