High spatial resolution single multiwalled carbon nanotube electrode for stimulation, recording, and whole cell voltage clamping of electrically active cells
High spatial resolution single multiwalled carbon nanotube electrode for stimulation, recording, and whole cell voltage clamping of electrically active cells
复制标题
DOI：
10.1063/1.3247885
复制
发表时间：
2009-10-12
影响因子：
4
通讯作者：
Nguyen, Cattien V.
中科院分区：
文献类型：
--
作者：
de Asis, Edward D., Jr.;Leung, Joseph;Nguyen, Cattien V.
我们报道了使用直径30 nm的单个多壁碳纳米管电极(sMWNT电极)尖端对肌肉纤维的刺激、记录和电压钳。由于进入电阻较低，与玻璃微吸管相比，sMWNT电极更有效地进行细胞外和细胞内刺激。SMWNT电极记录场电位和动作电位，并对单根纤维进行全电池电压钳制。(C)2009年美国物理研究所。[DOI：10.1063/1.3247885]
We report the stimulation, recording, and voltage clamp of muscle fibers using a 30 nm diameter single multiwalled carbon nanotube electrode (sMWNT electrode) tip. Because of the lower access resistance, the sMWNT electrode conducts extracellular and intracellular stimulation more efficiently compared to glass micropipettes. The sMWNT electrode records field potentials and action potentials and performs whole cell voltage clamping of single fibers. (C) 2009 American Institute of Physics. [doi:10.1063/1.3247885]