POSITION-EFFECT VARIEGATION AND THE NEW BIOLOGY OF HETEROCHROMATIN

POSITION-EFFECT VARIEGATION AND THE NEW BIOLOGY OF HETEROCHROMATIN
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DOI:
10.1016/s0959-437x(05)80055-3
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发表时间:
1994-04-01
影响因子:
4
通讯作者:
KARPEN, GH
KARPEN, GH
中科院分区:
生物学2区
文献类型:
--
作者:
KARPEN, GH

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位置效应杂色现象长期以来被用作真核生物中染色体位置对基因表达的重要性的证据。在过去几年中发表的调查表明,位置效应杂色是由多种机制引起的,并且可以用许多模型系统直接检验假设。
The phenomenon of position-effect variegation has long been used as evidence for the importance of chromosome position to gene expression in eukaryotes. Investigations published within the past few years demonstrate that position-effect variegation is caused by multiple mechanisms, and that direct tests of hypotheses are possible with numerous model systems.