Metabolic Products of Aspergillus terreus. IX. Biosynthesis of Butyrolactone Derivatives isolated from Strains IFO 8835 and 4100
Metabolic Products of Aspergillus terreus. IX. Biosynthesis of Butyrolactone Derivatives isolated from Strains IFO 8835 and 4100
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DOI：
10.1248/cpb.31.1528
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发表时间：
1983-05
影响因子：
1.7
通讯作者：
K. Nitta;N. Fujita;T. Yoshimura;K. Arai;Yuzuru Yamamoto
中科院分区：
文献类型：
--
作者：
K. Nitta;N. Fujita;T. Yoshimura;K. Arai;Yuzuru Yamamoto
从土曲霉IFO 4100中分离得到两个新的丁内酯I衍生物，并确定了结构。通过对土曲霉IFO 8835的生长或静止细胞施用潜在的中间体并通过酶促研究，建立了从苯丙氨酸到丁内酯I的代谢途径。鉴定了三种参与生物合成的酶。
Two new derivatives of butyrolactone I were isolated from Aspergillus terreus IFO 4100, and the structures were determined. A metabolic pathway from phenylalanine to butyrolactone I was established by administration of potential intermediates to growing or resting cells of Aspergillus terreus IFO 8835 and by enzymatic studies. Three enzymes involved in the biosynthesis were identified.