Carboxamide versus sulfonamide in peptide backbone folding: a case study with a hetero foldamer.
Carboxamide versus sulfonamide in peptide backbone folding: a case study with a hetero foldamer.
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DOI：
10.1021/ol4002762
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发表时间：
2013-03
期刊：
影响因子：
5.2
通讯作者：
Veera V. E. Ramesh;Sangram Kale;Amol S. Kotmale;Rupesh L. Gawade;V. Puranik;P. R. Rajamohanan;G. Sanjayan
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文献类型：
--
作者：
Veera V. E. Ramesh;Sangram Kale;Amol S. Kotmale;Rupesh L. Gawade;V. Puranik;P. R. Rajamohanan;G. Sanjayan
已经观察到两组非常相似的含有羧酰胺和磺酰胺的杂折叠体的氢键模式显著不同。虽然这两个折叠体保持构象有序，氢键模式和骨干螺旋旋向直径不同。
Strikingly dissimilar hydrogen-bonding patterns have been observed for two sets of closely similar hetero foldamers containing carboxamide and sulfonamides at regular intervals. Although both foldamers maintain conformational ordering, the hydrogen-bonding pattern and backbone helical handedness differ diametrically.