INCIDENCE OF EPILEPSY IN CHILDREN - FOLLOW-UP-STUDY 3 YEARS AFTER 1ST SEIZURE
INCIDENCE OF EPILEPSY IN CHILDREN - FOLLOW-UP-STUDY 3 YEARS AFTER 1ST SEIZURE
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DOI：
10.1111/j.1528-1157.1978.tb04500.x
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发表时间：
1978-01-01
期刊：
影响因子：
5.6
通讯作者：
BERGFORS, PG
中科院分区：
文献类型：
--
作者：
BLOM, S;HEIJBEL, J;BERGFORS, PG
对瑞典某县的癫痫发病率进行了前瞻性流行病学研究。在发病期间对52,252名0-15岁儿童进行了研究。74名儿童在2月1日首次癫痫发作。1973年至1974年1月31日，3年后重新检查。在随访中，43名儿童被归类为癫痫，发病率为82/10万。最常见的癫痫类型为：原发性全身性癫痫，占12/43 (27.9%)；部分性癫痫，11/43 (25.6%)；儿童期良性癫痫伴中央颞叶放电，11/43（25.6%）。原发性全身性癫痫组的初始脑电图表现对预后的意义较低。再次发作的儿童数量和只发作一次的儿童数量之间没有差异。根据临床和脑电图的发现，一些组往往比其他组有更大的复发性癫痫发作的风险。这些危险人群是围产期并发症或脑畸形和精神运动迟缓儿童、部分癫痫发作儿童、缺席和3/s峰波放电儿童和儿童期良性癫痫儿童。
A prospective epidemiological study of the incidence of epilepsy was performed in a Swedish county. During the incidence period 52,252 children aged 0-15 yr were studied. Seventy-four children who had their 1st seizure during Feb. 1. 1973 to Jan. 31, 1974 were reexamined 3 yr later. Forty-three children were classified as having epilepsy at the followup, which gave an incidence of 82/100,000. The most frequent types of epilepsy found were: primary generalized epilepsy, 12/43 (27.9%); partial epilepsies, 11/43 (25.6%); and benign epilepsy of childhood with centrotemporal discharges, 11/43 (25.6%). The prognostic significance of the initial EEG findings in the group with primary generalized epilepsy was low. No differences were found between the number of children who had further seizures and the number of children who had only 1 seizure. On the basis of clinical and EEG findings some groups tended to run a greater risk of developing recurrent seizures than others. These risk groups were children with perinatal complications or cerebral malformations and psychomotor retardation, children with partial seizures, children with absences and 3/s spike-and-wave discharges and children with benign epilepsy of childhood.